Use of HIV Post-Exposure Prophylaxis Among Men Who Have Sex With Men in Shenzhen, China: A Serial Cross-Sectional Study

Wang, Yao; Liu, Shaochu; Zhang, Yan; Tan, Wenfeng; Xie, Wei; Gan, Yongxia; Zheng, Chenli; Li, Hao; Yang, Zheng; Jiang, Lijuan; Chen, Lin; Zhao, Jin

doi:10.1007/s10461-022-03673-x

Cited by 6 publications

(4 citation statements)

References 26 publications

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“…The only two studies assessing nPEP showed that MSM who were married or cohabiting, had an HIV-positive sexual partner, and residing in Shenzhen were barriers. However, having an 'HIV status unknown' sexual partner and multiple sexual partners (≥2) were facilitators [24,35].…”

Section: Demographic and Socio-economic Characteristics Of Participantsmentioning

confidence: 99%

“…One study showed increasing HIV knowledge scores were associated with higher acceptability of PrEP [23]. One study showed being interested in initiating PrEP was positively associated with nPEP uptake [35].…”

Section: Awareness and Knowledgementioning

confidence: 99%

“…Another study, conducted in Ghana, showed that FSWs who were screened for STIs and had anal sex were more likely to use PrEP [33]. A study conducted in Shenzhen, China, showed that having sexual intercourse with women, preferring to find sexual partners in MSM venues, using Viagra, and receiving HIV-related services in clinics or MSM venues were all positively associated with nPEP uptake, whereas condom use in anal sex, lubricant use in annal sex, and rush popper use were all negatively associated with nPEP uptake [35].…”

Section: Behavioral Factorsmentioning

confidence: 99%

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Current Perspectives on the Determinants of Acceptability of Pre-Exposure Prophylaxis and Nonoccupational Post-Exposure Prophylaxis among People at Risk for HIV: A Scoping Review

Zhou

Assanangkornchai

2022

IJERPH

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Pre-exposure prophylaxis (PrEP) and nonoccupational post-exposure prophylaxis (nPEP) were found to be effective HIV biomedical interventions. However, several barriers to acceptance of these interventions were discovered among populations at risk for HIV, and the Coronavirus Disease 2019 (COVID-19) pandemic may also exacerbate these. The current scoping review aims to update information in regards to facilitators and barriers for PrEP and nPEP acceptability among key populations collected in the past two years and to identify any existing knowledge gaps during the time of the COVID-19 pandemic. Of 1453 studies retrieved, 16 met the final inclusion criteria. The review synthesized a range of individual, PrEP-specific, psychosocial, and health system factors that may affect the acceptability of PrEP or nPEP. The conclusion from this scoping review is that more research is needed to enable a comprehensive understanding of the determinants of acceptability of PrEP and nPEP in the context of COVID-19, particularly among PWID and FSWs.

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Section: Demographic and Socio-economic Characteristics Of Participantsmentioning

confidence: 99%

Section: Awareness and Knowledgementioning

confidence: 99%

Section: Behavioral Factorsmentioning

confidence: 99%

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Current Perspectives on the Determinants of Acceptability of Pre-Exposure Prophylaxis and Nonoccupational Post-Exposure Prophylaxis among People at Risk for HIV: A Scoping Review

Zhou

Assanangkornchai

2022

IJERPH

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“…Substantial evidence has established an association between PEP utilization and risk behaviors among MSM (16)(17)(18). The engagement in risk behaviors prompts MSM to use PEP, yet whether the utilization of PEP has an impact on risk behaviors of MSM remains unknown.…”

Section: Introductionmentioning

confidence: 99%

Utilization of post-exposure prophylaxis potentially contributed to the changes of risk behaviors among men who have sex with men in China

Su,

Liu,

et al. 2024

Front. Public Health

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BackgroundThe HIV infection status among men who have sex with men (MSM) in China is a cause for concern. Post-exposure prophylaxis (PEP) serves as a highly effective biomedical preventive measure against HIV infection. Substantial evidence has established an association between PEP utilization and risk behaviors among MSM, but whether the utilization of PEP has an impact on risk behaviors remains unknown. This study sought to elucidate the impact of PEP usage on risk behaviors among MSM and provide recommendations for developing targeted HIV prevention programs.MethodsA cohort study was conducted in Qingdao, China, from April 2021 to January 2022. Participants were enlisted by volunteers from community-based organizations through a snowball sampling method. Face-to-face interviews were conducted to collect sociodemographic and behavioral information of participants. The study encompassed a retrospective investigation, baseline survey, and follow-up survey, representing periods before, during, and after PEP usage, respectively. Generalized estimating equations, fitting a Poisson regression model, were applied to scrutinize changes in risk behaviors of MSM during and after PEP usage, in comparison to before PEP usage.ResultsA total of 341 MSM were recruited in the cohort study, with 179 individuals completing the follow-up survey. In comparison to before PEP usage, there was a significant increase in the proportion of Rush Popper usage (17.6% vs. 23.8% vs. 29.6%) and commercial sexual partners (10.9% vs. 17.6% vs. 21.8%) among MSM during and after PEP usage. Before PEP usage, 88.7% of MSM reported having ≥3 temporary sexual partners in the last 6 months. This proportion exhibited no significant change during PEP usage (91.8%), but it significantly increased to 97.8% after PEP usage (P < 0.05). Notably, there was a significant decrease in group sex during and after PEP usage compared to before PEP usage (30.8% vs. 21.4% vs. 21.2%).ConclusionThe utilization of PEP may impact risk behaviors among MSM, potentially leading to increased Rush Popper usage, temporary sexual partners, and commercial sexual partners after PEP usage, accompanied by a decrease in group sex. Further research is imperative to elucidate the impact of PEP utilization on MSM and develop targeted HIV prevention programs.

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The Impact of Providing Free HIV Self-testing on Sexual Risk Behaviors Among Men who have Sex with Men in Hunan, China: A Randomized Controlled Trial

et al. 2022

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Use of HIV Post-Exposure Prophylaxis Among Men Who Have Sex With Men in Shenzhen, China: A Serial Cross-Sectional Study

Cited by 6 publications

References 26 publications

Current Perspectives on the Determinants of Acceptability of Pre-Exposure Prophylaxis and Nonoccupational Post-Exposure Prophylaxis among People at Risk for HIV: A Scoping Review

Current Perspectives on the Determinants of Acceptability of Pre-Exposure Prophylaxis and Nonoccupational Post-Exposure Prophylaxis among People at Risk for HIV: A Scoping Review

Utilization of post-exposure prophylaxis potentially contributed to the changes of risk behaviors among men who have sex with men in China

The Impact of Providing Free HIV Self-testing on Sexual Risk Behaviors Among Men who have Sex with Men in Hunan, China: A Randomized Controlled Trial

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