Use of Impella Recover LP 2.5 in elective high risk percutaneous coronary intervention

High-risk PCI in acute coronary syndromes with Impella LP 2.5 device support

“…On the other hand, one single-center and two multicenter studies showed that 30-day mortality ranges from 3.7% to 10% in poor surgical candidates undergoing elective high-risk PCI under Impella LP 2.5 support [32][33][34]. The 30-day mortality of 2.86% observed in our study compares favorably with those results and demonstrates the safety of this interventional approach in high-risk patients for both PCI and CABG.…”

Incidence and prognosis of vascular complications after percutaneous placement of left ventricular assist device

“…26 The Europella registry included 144 consecutive patients, and rates of vascular complications were 4.0% at 30 days. 8 24 noted that the rate of vascular operations in the Impella 2.5 arm was no different than that of the IABP arm (but they did not quote the limb ischemia rate) and concluded that there was no difference associated with the use of the larger sheath. Pershad et al 28 noted a 6% vascular complications for patients in the PROTECT II Trial (Table VI).…”

“…Heroic limb salvage measures may not be an appropriate path in this very sick group of patients with very limited survival. 23 11 O'Neill 24 10 Lauten 25 4 Current study 17…”

Use of the Impella 2.5 in High-Risk Percutaneous Coronary Intervention

“…8,9 In the United States, several small trials 5,6,[9][10][11][12] have been completed or are underway to evaluate the Impella 2.5. Abiomed has sponsored several of these trials, including PROTECT I, PROTECT II, RECOVER I, RECOVER II, and ISAR-SHOCK.…”