Use of ion-trap liquid chromatography–mass spectrometry to screen and confirm drug residues in aquacultured products

Analysis of veterinary drug residues in shrimp: A multi-class method by liquid chromatography–quadrupole ion trap mass spectrometry

“…A significant advantage of MS n analysis is the reduction of background noise, thus both high specificity and sensitivity can be achieved. Recent studies have demonstrated the use of this type of mass spectrometry on confirmation of veterinary drugs [9,15,20,21]. Thus, LC-QIT-MS was chosen for this screening/confirmatory method.…”

Comparative evaluation between capillary electrophoresis and high-performance liquid chromatography for the analysis of florfenicol in plasma

“…A number of chromatographic methods have been described for quantitative determination of florfenicol in biological fluids. These include gas chromatography [4,5] and liquid chromatography-mass spectrometry [6][7][8][9]. More recently, micellar electrokinetic capillary chromatographic separation of florfenicol and florfenicol amine in pharmaceutical formulations has been reported with modified borate buffer containing sodium dodecyl sulphate [10].…”

Gold Magnetic Nanoparticles-based Chemiluminescent Immunoassay for Detection of Chloramphenicol in Milk

“…Conventional methods like microbiological methods [5] were not sensitive for CAP and were totally obsolete. Gas/liquid chromatography (GC/LC) [6][7] and gas/liquid chromatography-mass spectrometry (GC-MS/LC-MS) [8][9][10] are internationally recognized but expensive, complicated to operate, and not suitable for detecting lots of samples. Immunoassays including radio immunoassay (RIA) [11], enzyme-linked immunosorbent assay (ELISA) [12][13] have been reported frequently to screen CAP.…”