Use of Lactic Dehydrogenase for Detection of Avian Leukosis

Wallbank, Alfred M.; Sahl, Jacob; Hubben, K; Hollister, Charles J.; Sperling, F. George; Stubbs, E. L.

doi:10.1038/201844b0

Nature

1964

DOI: 10.1038/201844b0

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Use of Lactic Dehydrogenase for Detection of Avian Leukosis

Alfred M. Wallbank

Jacob Sahl

K Hubben

et al.

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1965

2010

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Cited by 5 publications

(1 citation statement)

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“…Data published on Rous sarcoma virus (RSV) (1,5,8) , the California strain of avian lymphomatosis ( Rubin's RIF virus) (9) , and the Stubbs-Furth strain of sarcoma and erythroblastosis (Strain 13) virus (S13V) (10) indicate all of these viruses were sensitive to ether. In addition, RSV and S13V were also inactivated by chloroform.…”

mentioning

confidence: 98%

Sensitivity of Strain R Avian Erythroblastosis Virus to Ether and Chloroform.

Wallbank

Stubbs

1965

Experimental Biology and Medicine

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mentioning

confidence: 98%

Sensitivity of Strain R Avian Erythroblastosis Virus to Ether and Chloroform.

Wallbank

Stubbs

1965

Experimental Biology and Medicine

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Lymphoid leukosis viruses, their recognition as ?persistent? viruses and comparisons with certain other retroviruses of veterinary importance

Darcel¹

1996

Veterinary Research Communications

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Diseases caused by lymphoid leukosis virus (LLV), a retrovirus, take a long time after infection to develop and have a wide variety of pathological manifestations. This long latent period is characteristic of 'persistent virus infections'. Disease produced by LLV infection and its underlying mechanisms is compared with 'persistent' infections caused by other retroviruses in birds and mammals of veterinary importance. The diseases considered for comparison are those caused by reticuloendotheliosis, feline leukaemia, bovine leukosis and equine infectious anaemia viruses. There are significant changes in the immunological status in all diseases caused by these viruses. LLV infections follow this trend with, in manifestations of neoplastic disease, a perturbation of the normal switch that occurs from IgM to IgG synthesis. There are also indications of other immunological disturbances. Factors other than immunological disturbances may contribute to the length of time after infection required for the many forms of LLV infection to appear. Such additional factors may include the operation of 'biological clocks', such as the arrival of sexual maturity, and also the very nature of retroviruses. These factors, like the immunological changes, play major roles in the maintenance and progression of persistent retrovirus infections.

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Über die Lactat-Dehydrogenase-Konzentration im Blut leukosekranker Hühner1,2

Gessler

2010

Zentralblatt Für Veterinärmedizin Reihe A

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Use of Lactic Dehydrogenase for Detection of Avian Leukosis

Cited by 5 publications

References 3 publications

Sensitivity of Strain R Avian Erythroblastosis Virus to Ether and Chloroform.

Sensitivity of Strain R Avian Erythroblastosis Virus to Ether and Chloroform.

Lymphoid leukosis viruses, their recognition as ?persistent? viruses and comparisons with certain other retroviruses of veterinary importance

Über die Lactat-Dehydrogenase-Konzentration im Blut leukosekranker Hühner1,2

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