Use of Lincomycin-Impregnated Demineralized Freeze-Dried Bone Allograft in the Periodontal Defect After Third Molar Surgery

Khorshidi, Hooman; Shahidi, Shoaleh; Gholami, Mahdi; Kalbasi, Saman; Khayati, Adell

doi:10.1016/j.joms.2013.11.028

Cited by 23 publications

(20 citation statements)

References 37 publications

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“…22,23 On the other hand; previous studies and our study demonstrate higher osteoblast counts, enhanced bone formation 19 , high tolerance by bone 17,18 , and no histological damage. 16 Cytotoxicity may associated with dose, concentration, the type of antimicrobial and exposure time.…”

supporting

confidence: 58%

Effect of Local Rifamycin Application on Expression of BMP-2 and Bone Regeneration

Ün¹,

Özeç²,

Taşdemir³

et al. 2017

Cumhuriyet Dental Journal

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Objectives: The aim of this study was to evaluate effect of local rifamycin application on BMP-2 expression and bone healing.Materials and Methods: A standardized 5.0-mm-diameter critical size bone defect was created mandible angulus region. In the control group (8 rats) defects were left empty. In the Group 1 (n=8 rats) defect was irrigated with rifamycin solution and 25 mg rifamycin solution injected defect area at 1, 3, 7 days after surgery. In the group 2 (n=8 rats) defects were grafted with a gelatin sponge mixed 25 mg rifamycin solution. Rats were sacrificed at 21 days after surgery. Histological slides were prepared from defect site for both immunohistochemical analysis (bone morphogenetic protein-2 (BMP-2) antibody) and histomorphometric analysis. Data were analyzed using Mann Whitney U and Kruskall Wallis test.

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supporting

confidence: 58%

Effect of Local Rifamycin Application on Expression of BMP-2 and Bone Regeneration

Ün¹,

Özeç²,

Taşdemir³

et al. 2017

Cumhuriyet Dental Journal

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“…Rejected studies at this stage and rationale for rejection are listed in http://www.joponline.org/doi/suppl/10.1902/jop.2015.150363/suppl_file/150363_suptab1.pdf in online Journal of Periodontology . Finally, 16 RCTs 29–44 were included in the systematic review, of which 10 29–38 could be analyzed by NMA.…”

Section: Resultsmentioning

confidence: 99%

“…A total of 16 RCTs are included in this review and subgrouped according to the type of M3M removal techniques as follows: 1) regenerative/grafting procedures, 10 studies; 29–38 2) flap design, three studies; 39–41 3) type of suturing, one study; 42 and 4) periodontal care of M2M, two studies 43 , 44 …”

Section: Resultsmentioning

confidence: 99%

“…In the regenerative/grafting procedures group, nine 29‐34,36‐38 of 10 29–38 studies compared the test intervention to a standard control, whereas one study compared two different guided tissue regeneration (GTR) techniques 35 . Eight of nine studies reported some adjunctive clinical benefits of regenerative/grafting therapies in terms of CALg and PDr compared to a standard control.…”

Section: Resultsmentioning

confidence: 99%

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Effect of Surgical Intervention for Removal of Mandibular Third Molar on Periodontal Healing of Adjacent Mandibular Second Molar: A Systematic Review and Bayesian Network Meta‐Analysis

Barbato

Kalemaj

Buti

et al. 2016

Journal of Periodontology

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To the best of the authors' knowledge, the present review is the first one to evaluate quantitatively and qualitatively the effect of different interventions on periodontal healing distal to the second molar after extraction of the third molar. GTR-based procedures with or without combined grafting therapies provide some adjunctive clinical benefit compared to standard non-regenerative/non-grafting procedures. However, the overall low quality of evidence suggests a low degree of confidence and certainty in treatment effects. Evidence on variations of surgical M3M removal techniques based on flap design, type of suturing, and periodontal care of M2M is limited both qualitatively and quantitatively.

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“…9 Socket preservation or guided bone regeneration (GBR) now included in the procedure of wisdom tooth removal to eliminate and prevent pocket formation on the distal of second molar. 10,11 A study by Zwahlen et al 12 found using guided tissue regeneration with different membrane in wisdom tooth socket is satisfying with an uneventful healing phase. In this current case report, the author tried to regenerate bone on distal root surface of the second molar that would be exposed after wisdom tooth removal.…”

Section: Introductionmentioning

confidence: 99%

Third Molar Socket Grafting after Surgical Extraction to prevent Periodontal Pocket Formation

Al-Juboori¹,

Yi²

2015

International Journal of Experimental Dental Science

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There is an incidence of periodontal pocket formation and gingival recession on the distal of the lower second molar due to bone defect after third molar surgical removal. Patient referred suffering from recurrent pericoronities; after clinical and radiographic examination, the lower left 3rd molar is partially erupted and angulated in mesial direction. The radiograph shows there is bone deficiency on the distal of the adjacent 2nd molar. After 3rd molar surgical removal, cancellous bone graft placed on the socket with guided bone regeneration (GBR) procedure and complete primary closure with rotational flap. Patient follow-up after 3 and 6 months, bone formation observed on the distal of 2nd molar with the absence of periodontal pocket. Third molar socket bone grafting with cancellous allograft may be a predictable procedure to prevent periodontal pocket on the distal of the second molar.

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Use of Lincomycin-Impregnated Demineralized Freeze-Dried Bone Allograft in the Periodontal Defect After Third Molar Surgery

Cited by 23 publications

References 37 publications

Effect of Local Rifamycin Application on Expression of BMP-2 and Bone Regeneration

Effect of Local Rifamycin Application on Expression of BMP-2 and Bone Regeneration

Effect of Surgical Intervention for Removal of Mandibular Third Molar on Periodontal Healing of Adjacent Mandibular Second Molar: A Systematic Review and Bayesian Network Meta‐Analysis

Third Molar Socket Grafting after Surgical Extraction to prevent Periodontal Pocket Formation

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