Use of Living Donors for Renal Homotransplantation

Abstract

The use of volunteer living donors to patient (Table 1). Of the 40 donors, 27 were either provide kidneys for renal homotransplanta-Parents or siblings. The other 13 were not genetically related to the recipient. In the last group, there were has many and lega1 imthree wives, nine convicts, and one volunteer who plications. The infliction of major operative responded to a public appeal (Table h3uma upon healthy well-motivated donors A mass of experimental evidence can be cited in cannot be dismissed lightly since the chance support of the position that homografts are tolerated for ultimate viability of the homograft in its better and for a longer period of time if the donor new environment is highly speculative. the and recipient subjects are closely related. In humans a similar but less incontrovertible tendency has been long run, justification for continued use Of noted.' In our experience, the incidence of success volunteer donors depends upon the demonhas been greatest with mother-to-offspring donastration that the donor operation carries a tions, next with siblings, and lowest with donations negligible risk and that the benefit for the from unrelated volunteers. recipient patients is substantial and pre-

Comparing Surgical Complications of Donors and Recipients in Retroperitoneoscopic versus Mini-Incision Donor Nephrectomy: A Single-Center Experience

“…Open lumbar flank incision with a retroperitoneal approach to the kidney has been a standard technique for the living donation for decades [14,15]. It is safe regarding the quality of the donated kidney and relatively easy to perform due to an optimal access in terms of space.…”

Laparoscopic Live Donor Nephrectomy: Rationale, Techniques, and Implications

“…The ODN operation has been refined incrementally over the past 40 years, yet is substantially similar to the first procedure performed 45 years ago. The ODN is typically performed through a flank incision using either a rib‐resecting or a rib‐sparing retroperitoneal approach (6,7). Several variations exist, however.…”

The Role of Organ Transplantation in Pediatrics

“…27,49 To date there have been no reported deaths in living volunteers. The high degree of safety with which nephrectomy can be carried out is probably ascribable to two factors.…”