Use of ^99mTc-HMPAO in Estimating the Antihypertensive Therapy Impact on the Cerebral Perfusion in Patients with Arterial Hypertension Associated with Diabetes Mellitus Type 2

Abstract

The article is devoted to the estimation of the impact of hypotensive therapy on the state of cerebral perfusion in patients with AH, associated with type 2 DM using99mTc-HMPAO brain SPECT. It has been shown that the signs of the brain hypoperfusion and reduced cerebrovascular reserve are observed in patients with AH in combination with type 2 DM even when focal neurological symptoms are absent. Using99mTc-HMPAO brain SPECT it has been found that carvedilol therapy of about 6 months has a positive effect on the cerebral perfusion and cerebrovascular reserve status in these patients.