Use of macular lenses in patients with age-related macular degeneration

Бикбов, М.М.; Orenburkina, O.I.; Babushkin, A.E.; Burkhanov, Yu.K.

doi:10.17116/oftalma202013603187

Cited by 2 publications

(2 citation statements)

References 16 publications

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“…13 Literature shows a new trend towards intraocular implantation of prisms within the capsular bag after phacoemulsification. 14 Contrary to our results, Smith et al compared three groups for AMD visual rehabilitation. They found that Prism spectacles were no more effective than conventional spectacles in patients with AMD.…”

Section: Discussioncontrasting

confidence: 97%

Effectiveness of Prism Spectacles in Patients with Age Related Macular Degeneration: A randomized control trial study

Tanveer¹,

Kiran²,

Hussain³

et al. 2022

pak J Ophthalmol

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Purpose: To compare between the use of prism and the spectacles without prism in improving near vision, distance vision and quality of life in patients with AMD. Study Design: Randomized control trial. Place and Duration of Study: Al-Shifa Trust Eye Hospital, from October 2021 to April 2022. Methods: Eighty-eight patients with AMD were selected and 44 patients were included in intervention group and control group each. Both interventional and control groups underwent Visual acuity (VA) for distance and near. VF-25 questionnaire was filled to evaluate quality of life (VFQoL). After prescribing prisms and simple glasses without prisms, both groups were called for a follow-up after one week and one month. VF-25 questionnaire was filled again. IBM SPSS was used for statistics. Categorical variables were presented by the frequencies and percentages. Continuous variables were presented by mean and standard deviation. Results: There were 63.64% males. Mean age of subjects was 67.28 + 8.0. A repeated measure ANOVA determined that mean VA for distance, near (for single opto-type and continuous text) and quality of life of intervention group and control group increased from pre-intervention to one month (p < .0005), and from pre-intervention to one week (p = <0.001), but not from one week to one month (p = >0.005).Mean improvement in near and distance vision was significant better in intervention group than the control group (p = < 0.001). Conclusion: There was statistically significant improvement in near, distance vision and quality of life with the use of prism in AMD.

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Section: Discussioncontrasting

confidence: 97%

Effectiveness of Prism Spectacles in Patients with Age Related Macular Degeneration: A randomized control trial study

Tanveer¹,

Kiran²,

Hussain³

et al. 2022

pak J Ophthalmol

View full text Add to dashboard Cite

show abstract

“…Alternatively, the doctor may perform photodynamic laser therapy by injecting the light-sensitive drug verteporfin ( Visudyne ) into the bloodstream, which is absorbed by abnormal blood vessels [ 208 ]. In addition, there are adjuvant devices such as special lenses or electronic systems for creating larger images of nearby things, which can help those who have vision loss due to macular degeneration and maximize their remaining vision [ 209 ].…”

Section: Current Therapy For Retinal Degenerationmentioning

confidence: 99%

The interplay of autophagy and oxidative stress in the pathogenesis and therapy of retinal degenerative diseases

et al. 2022

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Oxidative stress is mainly caused by intracellular reactive oxygen species (ROS) production, which is highly associated with normal physiological homeostasis and the pathogenesis of diseases, particularly ocular diseases. Autophagy is a self-clearance pathway that removes oxidized cellular components and regulates cellular ROS levels. ROS can modulate autophagy activity through transcriptional and posttranslational mechanisms. Autophagy further triggers transcription factor activation and degrades impaired organelles and proteins to eliminate excessive ROS in cells. Thus, autophagy may play an antioxidant role in protecting ocular cells from oxidative stress. Nevertheless, excessive autophagy may cause autophagic cell death. In this review, we summarize the mechanisms of interaction between ROS and autophagy and their roles in the pathogenesis of several ocular diseases, including glaucoma, age-related macular degeneration (AMD), diabetic retinopathy (DR), and optic nerve atrophy, which are major causes of blindness. The autophagy modulators used to treat ocular diseases are further discussed. The findings of the studies reviewed here might shed light on the development and use of autophagy modulators for the future treatment of ocular diseases.

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Use of macular lenses in patients with age-related macular degeneration

Cited by 2 publications

References 16 publications

Effectiveness of Prism Spectacles in Patients with Age Related Macular Degeneration: A randomized control trial study

Effectiveness of Prism Spectacles in Patients with Age Related Macular Degeneration: A randomized control trial study

The interplay of autophagy and oxidative stress in the pathogenesis and therapy of retinal degenerative diseases

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