Use of "Material for Osteoplasty» in Pediatric Orthopaedics: Assessment of the Efficacy and Study of Biologic Processes

Abstract

New composite «material for osteoplasty» was used for the treatment of 70 children, aged from 1.5 to 15 years, with various orthopaedic pathology. "Material" consists of defatted spongy and cortical-spongy bone matrix soaked with copolymer containing bioactive drugs as well as fetal bone tissue. Preliminary testing showed that the suggested implants were of high firmness. To assess the stimulating effect of "material for osteoplasty" upon the process of bone tissue reparative regeneration, monitoring of regional microcirculation by ultrasound Doppler mapping was used in complex with other methods. Osteoconductive and osteoinductive characteristics of the implants were observed in 76% of cases. The results of ultrasound Doppler mapping showed good correlation with the morphologic picture.