2009
DOI: 10.1136/bmj.b566
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Use of melanotan I and II in the general population

Abstract: Is unlicensed, unregulated, and potentially harmful

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Cited by 51 publications
(38 citation statements)
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“…This is consistent with the risk profile of users of illegal products for tanning purposes, since these individuals are more likely than the general population to expose themselves to harmful doses of intense ultraviolet radiation by frequent and prolonged sun exposure or the use of tanning salons. 34 Moreover, such illegal products may contain other melanotropic agents or unidentified harmful components. The listing of skin premalignancies or malignancies as contraindications is a precautionary measure only, as up to now afamelanotide has not been reported to cause such conditions.…”
Section: Discussionmentioning
confidence: 99%
“…This is consistent with the risk profile of users of illegal products for tanning purposes, since these individuals are more likely than the general population to expose themselves to harmful doses of intense ultraviolet radiation by frequent and prolonged sun exposure or the use of tanning salons. 34 Moreover, such illegal products may contain other melanotropic agents or unidentified harmful components. The listing of skin premalignancies or malignancies as contraindications is a precautionary measure only, as up to now afamelanotide has not been reported to cause such conditions.…”
Section: Discussionmentioning
confidence: 99%
“…The association between exposure to HBV and having obtained advice from an SH/STI clinic is again suggestive of a role for sexual risk in infection, particularly as sexual transmission is the main route by which HBV is now acquired within the UK 48. The association between having anti-HBc and not injecting subcutaneously suggests that certain patterns of IPED use might be related to increased risk, as some IPEDs are only injected subcutaneously and others only intramuscularly, and many users take several types 3 8 12––14. Exposure to HCV, however, would appear to be associated with the injection of psychoactive drugs, an association that has been previously noted6; this finding might reflect more frequent injecting in this subgroup.…”
Section: Discussionmentioning
confidence: 99%
“…These drugs range from tanning drugs, such as ‘Melanotan-II’,12 to those used in body-building, such as human growth hormone 3 13. The most commonly injected and studied IPEDs are anabolic steroids (AS) 3 5.…”
Section: Introductionmentioning
confidence: 99%
“…Further studies have been conducted testing the drug in the treatment of erectile dysfunction, but to date the drug is unapproved outside clinical studies. The substance can illegally be obtained from the Internet or from gyms and sunbed parlours, without any medical control or restriction [5]. Several governmental drug-regulatory bodies have issued warnings [6] against the use of MT-II, and in the literature MT-II has been related to eruptive [7] and atypical naevi [8], melanoma [9], melanonychia [10] and rhabdomyolysis [11].…”
Section: Introductionmentioning
confidence: 99%