Use of Mesoporous Molecular Sieves in the Production of Fine Chemicals: Preparation of Dihydroquinolinones of Pharmaceutical Interest From 2′‐Aminochalcones

Abstract

Product desorption has been controlled by optimizing catalyst pore structure and surface composition, together with a proper selection of solvent and reaction temperature.Process intensification for the synthesis of aryl-2,3-4(1H)-quinolinones of pharmaceutical interest has been achieved by preparing catalysts that allow the one pot synthesis of the dihydroquinolinones starting from 2'-nitrochalcones with excellent yields.