Use of minimal extracorporeal circulation improves outcome after heart surgery; a systematic review and meta-analysis of randomized controlled trials

Anastasiadis, Kyriakos; Antonitsis, Polychronis; Haidich, Anna‐Bettina; Argiriadou, Helena; Deliopoulos, Apostolos; Papakonstantinou, Christos

doi:10.1016/j.ijcard.2012.01.020

Cited by 118 publications

(95 citation statements)

References 80 publications

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“…In a recent meta-analysis of clinical trials including 24 studies with a total of 2,770 patients (56), the use of MECC in heart surgery resulted in improved short-term outcome as reflected by reduced mortality (P=0.02), postoperative myocardial infarction (P=0.03) and neurologic events (P=0.008) compared with conventional extracorporeal circulation.…”

Section: Non-surgical Techniquesmentioning

confidence: 99%

Acute respiratory distress syndrome after cardiac surgery

2016

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Acute respiratory distress syndrome (ARDS) is a leading cause of postoperative respiratory failure, with a mortality rate approaching 40% in the general population and 80% in the subset of patients undergoing cardiac surgery. The increased risk of ARDS in these patients has traditionally been associated with the use of cardiopulmonary bypass (CPB), the need for blood product transfusions, large volume shifts, mechanical ventilation and direct surgical insult. Indeed, the impact of ARDS in the cardiac population is substantial, affecting not only survival but also in-hospital length of stay and long-term physical and psychological morbidity. No patient undergoing cardiac surgery can be considered ARDS risk-free. Early identification of those at higher risk is crucial to warrant the adoption of both surgical and non-surgical specific preventative strategies. The present review focuses on epidemiology, risk assessment, pathophysiology, prevention and management of ARDS in the specific setting of patients undergoing cardiac surgery.

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Section: Non-surgical Techniquesmentioning

confidence: 99%

Acute respiratory distress syndrome after cardiac surgery

2016

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“…Не угасает интерес к исследованиям различных стра-тегий прямой реваскуляризации миокарда в аспекте их преимущества у пациентов с СД [36,[45][46][47][48].…”

Section: различные стратегии прямой реваскуляризации миокарда у пациеunclassified

“…Кардиология Cardiology реже развивалась острая почечная недостаточность в послеоперационном периоде и медиастиниты, короче было время лечения в отделении реанимации, длитель-ность госпитализации, отмечалось снижение 30-днев-ной смертности по сравнению с группой обычного ИК (p<0,05) [46].…”

Section: сахарный диабет Diabetes Mellitusunclassified

Myocardial revascularization in patients with coronary heart disease and type 2 diabetes

Безденежных

Sumin

2016

Diabetes mellitus

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The review discusses myocardial revascularization in patients with coronary heart disease and type 2 diabetes. The data presented include findings from recent research and international and national recommendations and provides evidence on the advantages of coronary artery bypass surgery over percutaneous coronary intervention for patients with diabetes mellitus, stable coronary artery disease and multiple coronary artery lesions. Type 2 diabetes remains a significant predictor of adverse long-term outcomes of coronary artery bypass surgery. Therefore, we review studies showing that different strategies of coronary revascularization and preoperative preparation can affect the results of coronary intervention in patients with diabetes.

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“…In a meta-analysis including 24 randomized studies of coronary artery bypass or aortic valve replacement, miniaturized biocompatible circuits led to lower risk of blood transfusion requirement (17.5% vs 43.1%), lesser neurologic events (2.3% vs 4%), lesser inotropic support, and lesser systemic inflammation, reflected in a shorter mechanical ventilation period, a shorter ICU stay, and more importantly lower hospital mortality (0.5% vs 1.7%). 18 Nevertheless, in cases of massive bleeding with difficult control, CPB provides the advantages of autotransfusion; rapid heterologous blood transfusion; delivery of cardioplegia for cardiac arrest; and, if needed, deep hypothermic circulatory arrest.…”

Section: Use Of Venoarterial Extracorporeal Membrane Oxygenation In Tmentioning

confidence: 99%

Cardiopulmonary Bypass and Extracorporeal Life Support for Emergent Intraoperative Thoracic Situations

Machuca

Cypel

Keshavjee

2015

Thoracic Surgery Clinics

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Use of minimal extracorporeal circulation improves outcome after heart surgery; a systematic review and meta-analysis of randomized controlled trials

Cited by 118 publications

References 80 publications

Acute respiratory distress syndrome after cardiac surgery

Acute respiratory distress syndrome after cardiac surgery

Myocardial revascularization in patients with coronary heart disease and type 2 diabetes

Cardiopulmonary Bypass and Extracorporeal Life Support for Emergent Intraoperative Thoracic Situations

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