Use of Mixed Methods Research in Research on Coronary Artery Disease, Diabetes Mellitus, and Hypertension

Campbell, David; Tam-Tham, Helen; Dhaliwal, Kirnvir K.; Manns, Braden; Hemmelgarn, Brenda R.; Sanmartin, Claudia; King‐Shier, Kathryn

doi:10.1161/circoutcomes.116.003310

Cited by 9 publications

(7 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In line with findings reported in recent reviews [8,26,34], many articles reported a convergent design and cited complementarity as the main rationale for mixing methods. In these studies, the findings of the quantitative and the qualitative components were used to enrich or elaborate on the findings of the other component or to provide further insights.…”

Section: Main Findingssupporting

confidence: 79%

A Methodological Review of Mixed Methods Research in Palliative and End-of-Life Care (2014–2019)

Fàbregues

Hong

Escalante-Barrios

et al. 2020

IJERPH

View full text Add to dashboard Cite

Mixed methods research has been increasingly recognized as a useful approach for describing and explaining complex issues in palliative care and end-of-life research. However, little is known about the use of this methodology in the field and the ways in which mixed methods studies have been reported. The purpose of this methodological review was to examine the characteristics, methodological features and reporting quality of mixed methods articles published in palliative care research. The authors screened all articles published in eight journals specialized in palliative care between January 2014 and April 2019. Those that reported a mixed methods study (n = 159) were included. The Good Reporting of a Mixed Methods Study (GRAMMS) criteria were used to assess reporting quality. Findings showed that 57.9% of the identified studies used a convergent design and 82.4% mentioned complementarity as their main purpose for using a mixed methods approach. The reporting quality of the articles generally showed a need for improvement as authors usually did not describe the type of mixed methods design used and provided little detail on the integration of quantitative and qualitative methods. Based on the findings, recommendations are made to improve the quality of reporting of mixed methods articles in palliative care.

show abstract

Section: Main Findingssupporting

confidence: 79%

A Methodological Review of Mixed Methods Research in Palliative and End-of-Life Care (2014–2019)

Fàbregues

Hong

Escalante-Barrios

et al. 2020

IJERPH

View full text Add to dashboard Cite

show abstract

“…Epidemiologic research has revealed that alcohol consumption is related to the risk of CHD incidence ( 33 ). Besides, diabetes and hypertension are the major risk factors for CHD incidence ( 34 ). However, no association was observed in drinkers and in CHD patients with diabetes or hypertension.…”

Section: Discussionmentioning

confidence: 99%

Effect of Cytochrome P450 Family 2 Subfamily R Member 1 Variants on the Predisposition of Coronary Heart Disease in the Chinese Han Population

Wang

Lin

Chen

et al. 2021

Front. Cardiovasc. Med.

View full text Add to dashboard Cite

Propose: Cytochrome P450 family 2 subfamily R member 1 (CYP2R1) variations can affect the activity of 25-hydroxylase, resulting in the deficiency of 25(OH)D, which leads to an increased incidence and mortality of coronary heart disease (CHD). The purpose is to assess the influence of CYP2R1 variants on CHD risk among the Chinese Han population.Methods: A total of 508 CHD patients and 510 healthy controls were enrolled. The MassARRAY platform completed genotyping of CYP2R1 variants. Odds ratios (ORs) with 95% confidence intervals (CI) were calculated using logistic regression analysis.Results: Rs6486205 (OR = 1.25, 95% CI: 1.05–1.50, p = 0.014), rs10741657 (OR = 1.29, 95% CI: 1.08–1.54, p = 0.005), and rs2060793 (OR = 1.27, 95% CI: 1.06–1.51, p = 0.009) were associated with the increased susceptibility to CHD in the whole subjects. Interestingly, the relationships between these variants and CHD risk were observed in the subjects with age >60 years, males or non-smoker. Additionally, the haplotypes Ars10741657Ars2060793 and Grs10741657Grs2060793 had the higher risk of CHD, and the combination (rs6486205 and rs10741657) was the best multi-locus model.Conclusion: Our study suggested the contribution of CYP2R1 polymorphisms to the increased CHD predisposition in the Chinese Han population. Furthermore, the risk association was related to confounding factors for CHD, including age, sex, and smoking. These findings might help to strengthen the understanding of the CYP2R1 gene in the occurrence of CHD.

show abstract

“…The strengths of our study are that we captured the experiences and preferences for hypertension management and potential usefulness of a mHealth or eHealth intervention among Black and Latinx populations. Few studies have applied mixed-methods to explore both medication adherence and the use of technology for managing hypertension [ 21 , 22 ]. Using a mixed-methods study design we elicited greater insights to medication adherence practices and interest in technology for a behavioral intervention, than using only quantitative methods.…”

Section: Discussionmentioning

confidence: 99%

Examining medication adherence and preferences for a lifestyle intervention among Black and Latinx adults with hypertension: a feasibility study

Dougherty

Burse

Butzner

et al. 2021

Pilot Feasibility Stud

View full text Add to dashboard Cite

Background Approximately 116.4 million adults in the USA have hypertension, and the rates of uncontrolled hypertension remain higher among racial and ethnic minorities. There is a need for effective interventions that promote healthy behaviors and long-term behavioral change in the management of hypertension. The primary objective of this study was to determine the feasibility of developing a lifestyle intervention that would assess hypertension management and the use of technology among Blacks and Latinx with hypertension. The secondary objective is to explore perceptions of community-based resources for hypertension and preferences for a lifestyle intervention for hypertension among Blacks and Latinx with hypertension. Methods In this explanatory mixed-methods study, quantitative data were collected using surveys, participants reported their use of technology and adherence to antihypertensive medication. Participants were Black and Latinx adults with hypertension living in Central Pennsylvania, USA. Qualitative data were obtained from semi-structured interviews and focus groups, and participants were asked about managing hypertension, local resources, and preferences for a behavioral intervention. Data were examined using summary statistics for quantitative data and thematic analysis for qualitative data. Results Black and Latinx participants (n=30) completed surveys for the quantitative study. The majority (75%) of participants self-reported being confident in managing their medication without help and remembering to take their medication as prescribed. Fewer participants (54.2%) reported using technology to help manage medication. There were 12 participants in the qualitative phase of the study. The qualitative findings indicated that participants felt confident in their ability to manage hypertension and were interested in participating in a lifestyle intervention or program based online. Some participants reported a lack of resources in their community, while others highlighted local and national resources that were helpful in managing high blood pressure. Conclusion This study provides important insights on barriers and facilitators for managing hypertension, current use of technology and interest in using technology to manage hypertension, and preferences for future lifestyle interventions among racial and ethnic minorities. This study also provides insights to the health needs and resources available in this community and how future behavioral interventions could be tailored to meet the needs of this community. The findings of this study will be used to inform the tailoring of future lifestyle interventions; specifically, we will include text messaging reminders for medication and to disseminate educational materials related to hypertension and provide resources to connect study participants with local and national resources.

show abstract

Use of Mixed Methods Research in Research on Coronary Artery Disease, Diabetes Mellitus, and Hypertension

Cited by 9 publications

References 40 publications

A Methodological Review of Mixed Methods Research in Palliative and End-of-Life Care (2014–2019)

A Methodological Review of Mixed Methods Research in Palliative and End-of-Life Care (2014–2019)

Effect of Cytochrome P450 Family 2 Subfamily R Member 1 Variants on the Predisposition of Coronary Heart Disease in the Chinese Han Population

Examining medication adherence and preferences for a lifestyle intervention among Black and Latinx adults with hypertension: a feasibility study

Contact Info

Product

Resources

About