2020
DOI: 10.1177/0003702820969192
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Use of Near-Infrared–Mid-Infrared Dual-Wavelength Spectrometry to Obtain Two-Dimensional Difference Spectra of Sesame Oil as Inactive Drug Ingredient

Abstract: The present study has investigated the transformation of sesame oil kept at low temperature during a definite period of time for refinement (called winterization) as an inactive drug ingredient by using two-dimensional difference spectra (2D-DS) analysis of spectra collected by a near-infrared (NIR) and mid-infrared (MIR) dual-wavelength spectrometer (NIR/MIR-DWS). The NIR and MIR spectra were measured nearly simultaneously from samples of sesame oil before and after winterization. The difference spectrum anal… Show more

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Cited by 2 publications
(2 citation statements)
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“…Winterization is a simple and cheap way of removing a wide array of fatty substances from vegetable oils. By applying the procedures described to winterize vegetable oils (Nergiz and Celikkale, 2011;Watari et al, 2020), we obtained a product enriched in AAs that we have used here to assess its possible antimicrobial effects and to further obtain a pure mixture of AAs. We focused our tests on those streptococcal pathogens (S. pyogenes and S. pneumoniae) involved in sore throat and middle ear pathologies and on two other nonstreptococcal species often provoking pathology in the middle ear (M. catarrhalis and H. influenzae).…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Winterization is a simple and cheap way of removing a wide array of fatty substances from vegetable oils. By applying the procedures described to winterize vegetable oils (Nergiz and Celikkale, 2011;Watari et al, 2020), we obtained a product enriched in AAs that we have used here to assess its possible antimicrobial effects and to further obtain a pure mixture of AAs. We focused our tests on those streptococcal pathogens (S. pyogenes and S. pneumoniae) involved in sore throat and middle ear pathologies and on two other nonstreptococcal species often provoking pathology in the middle ear (M. catarrhalis and H. influenzae).…”
Section: Discussionmentioning
confidence: 99%
“…The LO was then filtered and stored in stainless steel containers at 20 • C until bottling. Prior to testing, the sample was centrifuged at 12,000 rpm for 15 min and the supernatant was subjected to winterization, according to an already described method (Nergiz and Celikkale, 2011), to remove fatty substances and impurities and further stabilize its condition (Watari et al, 2020).…”
Section: Wlomentioning
confidence: 99%