Use of noninvasive ventilation in patients with amyotrophic lateral sclerosis

Abstract

NIPPV is used more than seven times as frequently as invasive ventilation in ALS patients. Patients who use NIPPV have more severe disease than those who do not use any respiratory intervention. Patients with lower income are less likely to use NIPPV, which raises concerns about disparities in the care of patients with ALS.

Accepting or declining non-invasive ventilation or gastrostomy in amyotrophic lateral sclerosis: patients’ perspectives

“…In quantitative studies, factors found to affect decisionmaking by pwALS in terms of NIV (and ventilation more generally) and gastrostomy include disease characteristics such as severity of symptoms [17]; demographic factors such as gender, age, educational level and IQ; and various psychological characteristics such as health beliefs, understanding of the illness, attachment to life, religiosity and mood (see [17][18][19][20][21][22][23]) as well as carer-rated everyday behavioural change indicative of executive dysfunction [17]. It has also been found that pwALS who indicate possible acceptance of NIV and gastrostomy early on in the disease trajectory are more likely to abide by their initial decision [24][25].…”

Amyotrophic Lateral Sclerosis and Oral Health

“…However, in ALS patients, the BiPAP system is most prevalent [24]. Noninvasive positive pressure ventilation use in ALS patients has been associated with prolonged survival rates [24]. In recent years nocturnal NIPPV use has become the treatment of choice for ALS patients suffering chronic respiratory insufficiency.…”

“…There are other forms of non-invasive assisted ventilation available. However, in ALS patients, the BiPAP system is most prevalent [24]. Noninvasive positive pressure ventilation use in ALS patients has been associated with prolonged survival rates [24].…”

“…In recent years nocturnal NIPPV use has become the treatment of choice for ALS patients suffering chronic respiratory insufficiency. The extent of NIPPV use in amyotrophic lateral sclerosis patients has not been widely studied [24]. Approximately three to five percent of ALS patients elected to have invasive ventilation [24].…”

“…The extent of NIPPV use in amyotrophic lateral sclerosis patients has not been widely studied [24]. Approximately three to five percent of ALS patients elected to have invasive ventilation [24]. Mechanical ventilatory support is provided via a tracheostomy, a surgically created opening in the trachea through which air is forced on an individualized, timed cycle.…”