Use of photodynamic therapy and acitretin in generalized eruptive keratoacanthoma of Grzybowski

Mlacker, Stephanie; Kaw, Urvashi; Maytin, Edward V.

doi:10.1016/j.jdcr.2017.06.013

Cited by 6 publications

(2 citation statements)

References 9 publications

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“…The data regarding the use of PDT for keratoacanthomas is however scarce and limited to case presentations or case series. While some authors show that PDT could be a good alternative for patients with keratoacanthomas (100,101), other authors suggest that keratoacanthomas could develop after PDT (102,103). Further research is therefore mandatory to support the usefulness of PDT for the treatment of keratoacanthomas.…”

Section: Updates In Pdt In the Treatment Of Other Precancerous Skin Lmentioning

confidence: 99%

Photodynamic therapy: A hot topic in dermato-oncology (Review)

et al. 2019

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Photodynamic therapy (PDT) is a modern, non-invasive therapeutic method used for the destruction of various cells and tissues. It requires the simultaneous presence of three components: a photosensitizer (PS), a light source and oxygen. Precancerous skin lesions are conditions associated with a high likelihood of malignant transformation to squamous cell carcinoma. Data available so far indicate that PDT is a promising treatment method which can be successfully employed in several medical fields including dermatology, urology, ophthalmology, pneumology, cardiology, dentistry and immunology. Numerous authors therefore have studied this technique in order to improve its efficacy. As a result, significant advancement has been achieved with regard to PSs and drug delivery systems. Substantial progress was also obtained with respect to PDT for the treatment of precancerous skin lesions, several authors focusing their efforts on the study of daylight-PDT and on identifying methods of decreasing technique-related pain. This review reports on the most recent findings in PDT, with emphasis on cutaneous precancerous lesions. Contents 1. Introduction 2. Photodynamic therapy-generalities 3. Updates in PDT components 4. Updates in PDT for the management of actinic keratoses 5. Updates in PDT for Bowen's disease and erythroplasia of Queyrat 6. Updates in PDT in the treatment of other precancerous skin lesions: Actinic cheilitis and keratoacanthoma 7. Updates in PDT for lichen sclerosus-a dermatosis with potential for malignant transformation 8. Discussion

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Section: Updates In Pdt In the Treatment Of Other Precancerous Skin Lmentioning

confidence: 99%

Photodynamic therapy: A hot topic in dermato-oncology (Review)

et al. 2019

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“…The treatment of generalized eruptive keratoacanthomas of Grzybowski does not exclude relapses of the disease and is performed with aromatic retinoids or cytostatics. In some cases, intralesional injections of interferon-α, applications of cytostatic drugs, electrocoagulation, cryo-and laser destruction, photodynamic therapy, and surgical tumor excision are employed [6][7][8][9].…”

Section: Discussionmentioning

confidence: 99%

Generalized eruptive keratoacanthomas of Grzybowski in the practice of a dermatologist: A case report

Kuklin¹,

Malishevskaya²,

Кохан³

et al. 2022

Our Dermatol Online

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The article deals with a case of the clinical observation of a rare disease: generalized eruptive keratoacanthomas of Grzybowski. The disease pattern is characterized by the presence of small, generalized, itchy papules on the skin of the face, eyelids, trunk, extremities, genitals, and oral and laryngeal mucosae. The authors present a case of their own clinical observation of multiple eruptive keratoacanthomas of the Grzybowski type in a fifty-year-old patient seeking medical advice from a dermatologist. The duration of the disease was 2.5 years and its occurrence was preceded by repeated visits to countries with excessive insolation, which may be considered an etiological factor in the development of the disease. The diagnosis was verified by the disease pattern and pathomorphological studies on a biopsy of the affected skin.

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Squamous Cell Carcinoma and its Precursors

Gupta,

Dirschka

2024

Rook's Textbook of Dermatology

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Squamous cell carcinoma (SCC) is the second commonest skin cancer and arises from epidermal keratinocytes or its appendages. The incidence of SCC has increased over the last five decades and is predicted to rise significantly over the next decade. SCC is predominantly a disease of white populations and is especially prevalent in this group in areas of high ambient sun exposure. Predisposing factors include male sex, immune suppression (particularly in those who are organ transplant recipients), sun exposure and advanced age. Precursor lesions such as actinic keratosis and Bowen disease may often be present and patients are more susceptible to developing other UV radiation‐induced skin cancers. SCC has a low rate of metastasis but this increases with SCCs displaying high‐risk features. All SCCs should undergo full clinicopathological correlation and high‐risk SCCs should be managed within a multidisciplinary setting with adequate tumour clearance as the main outcome.

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Use of photodynamic therapy and acitretin in generalized eruptive keratoacanthoma of Grzybowski

Cited by 6 publications

References 9 publications

Photodynamic therapy: A hot topic in dermato-oncology (Review)

Photodynamic therapy: A hot topic in dermato-oncology (Review)

Generalized eruptive keratoacanthomas of Grzybowski in the practice of a dermatologist: A case report

Squamous Cell Carcinoma and its Precursors

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