Use of Platelet-Rich Plasma for the Treatment of Dyspareunia in Postmenopausal Women

Romashchenko, Prof. Oksana; Grygorenko, Prof. Viacheslav; Biloholovska, Valentyna; Babych, Oleksandr; Melnykov, Prof. Sergii; Yakovenko, Liudmyla

doi:10.1016/j.jsxm.2022.08.114

Cited by 3 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Additionally, this study found that reduced dyspareunia was associated with desire, arousal, orgasm, lack of anticipatory anxiety, sexual initiative, lack of penetration, and satisfaction with sex. As highlighted in recent research, the literature states that dyspareunia reduces sexual desire in women [ 29 ]. Sexual desire is related to other highly correlated sexual health dimensions.…”

Section: Discussionmentioning

confidence: 99%

Comparative study of postpartum sexual function: Second-degree tears versus episiotomy outcomes

Fernández-Fernández,

de Medina-Moragas

2024

Arch Gynecol Obstet

View full text Add to dashboard Cite

Purpose The effects of episiotomy and second-degree tears on postpartum sexual function are key areas of enquiry in women’s health research. Episiotomy and second-degree tears are common procedures and injuries that occur during childbirth. Understanding their impact on post-childbirth sexuality is crucial to women’s overall well-being. This study aimed to examine the relationship between episiotomy, second-degree tears, and post childbirth sexuality. Methods A cross-sectional design was employed, including 83 women who gave birth to Cáceres in 2017. Participants were evaluated based on sociodemographic and sexual health factors. Results No significant differences were found in dyspareunia or sexual function between women who underwent episiotomies and those with second-degree tears. However, women who underwent episiotomies waited longer before resuming sexual activity after childbirth. Factors such as age, number of previous births, employment status, educational level, and breastfeeding status affected the timing and frequency of postpartum sexual activity. Conclusion Dyspareunia negatively affects various aspects of sexual function. When comparing episiotomy and second-degree tears, their impacts on postpartum sexual function were similar. However, episiotomy delays the resumption of sexual activity. Sociodemographic factors significantly influence postpartum sexual health. These findings highlight the importance of individualised interventions and support for new mothers during the postpartum period to address potential sexual health concerns.

show abstract

Section: Discussionmentioning

confidence: 99%

Comparative study of postpartum sexual function: Second-degree tears versus episiotomy outcomes

Fernández-Fernández,

de Medina-Moragas

2024

Arch Gynecol Obstet

View full text Add to dashboard Cite

show abstract

“…Ultimately, 12 studies (one RCT and 11 observational studies) were included in the qualitative synthesis. Six prospective single-arm studies [34][35][36][37][38][39] and one RCT assessed the efficacy of PRP on female SUI [40], while four prospective single-arm studies [41][42][43][44] and one retrospective single-arm study [12] assessed the efficacy of PRP on FSD. The step-by-step study selection process is illustrated in Figure 1, and the reference list of all excluded studies with reasons for exclusion is presented in Supplement Data S2.…”

Section: Study Selection Study Characteristics and Quality Assessmentmentioning

confidence: 99%

“…Regarding quality assessment, based on RoB-2, the included RCT was considered at high risk of bias (Supplement Data S3) [40]. Accordingly, the ten prospective studies [34][35][36][37][38][39][41][42][43][44] and one retrospective study [12] were considered at moderate risk of bias, based on the NOS (Supplement Data S4).…”

Section: Study Selection Study Characteristics and Quality Assessmentmentioning

confidence: 99%

Efficacy and Safety of Platelet-Rich Plasma Injections for the Treatment of Female Sexual Dysfunction and Stress Urinary Incontinence: A Systematic Review

Dankova,

Pyrgidis,

Tishukov

et al. 2023

Biomedicines

View full text Add to dashboard Cite

Introduction: There is no clear evidence in the literature that platelet-rich plasma (PRP) injections improve female sexual dysfunction (FSD) and female stress urinary incontinence (SUI). Objectives: A systematic review was performed to study the efficacy and safety of PRP injections in women with the above pathologies, as well as to explore the optimal dosing, frequency and area of injections, and duration of treatment. Methods: A systematic search on PubMed, Embase and the Cochrane Library database was performed, as well as sources of grey literature from the date of database or source creation to January 2023. After title/abstract and full-text screening, clinical studies on humans evaluating the efficacy of PRP in gynecological disorders using standardized tools were included. Risk of bias was undertaken with RoB-2 for randomized-controlled trials (RCT) and the Newcastle-Ottawa Scale (NOS) for observational studies. Results: Four prospective and one retrospective study explored FSD, while six prospective and one RCT evaluated female SUI. A total of 327 women with a mean age of 51 ± 12 years were included. For FSD, PRP significantly improved the Female Sexual Function Index (FSFI), the Vaginal Health Index (VHI) and the Female Sexual Distress score (FSDS). For SUI, PRP led to a significant improvement in the International Consultation on Incontinence Questionnaire—Short Form (ICIQ-SF) and the Urogenital Distress Inventory (UDI-6). The identified RCT reported a significantly higher mean score of ICIQ-SF (p < 0.05) and UDI-6 (p < 0.01) in the midurethral sling group compared to the PRP injections group. Regarding the risk of bias, the RCT was characterized by high risk, whereas the observational studies were of moderate risk. The protocol for PRP injections for FSD is the injection of 2 mL of PRP into the distal anterior vaginal wall once a month for 3 months. For female SUI, 5–6 mL of PRP should be injected into the periurethral area once a month for 3 months. Conclusions: Despite the promising initial results of PRP injections, the level of current evidence is low due to methodological issues in the available studies. It becomes clear that there is an emerging need for high-quality research examining PRP injections for the treatment of FSD and female SUI.

show abstract

Use of injection methods in genitourinary syndrome of menopause

Avin¹,

Суркичин

2023

Medicinskij alfavit

View full text Add to dashboard Cite

Genitourinary syndrome of menopause (GSM) is a set of symptoms of atrophy, the main cause of which are evolutive changes in the vulvovaginal and urethral regions. GSM is a common condition affecting up to 90 % of menopausal women. The main symptoms encountered in this syndrome include: dryness of the vulvovaginal area (more than 90 %), dyspareunia (78 %), itching (57 %) and burning (57 %). These symptoms, according to various questionnaires, strongly affect the quality of women’s life, as well as their sexual life. A review of GSM therapy with plasma therapy (PRP) and injection with hyaluronic acid was performed. The clinical observation and the process of managing patients with manifestations of GSM are described in detail. An analysis of the effectiveness and safety of injection techniques in GSM is considered.

show abstract

Use of Platelet-Rich Plasma for the Treatment of Dyspareunia in Postmenopausal Women

Cited by 3 publications

References 0 publications

Comparative study of postpartum sexual function: Second-degree tears versus episiotomy outcomes

Comparative study of postpartum sexual function: Second-degree tears versus episiotomy outcomes

Efficacy and Safety of Platelet-Rich Plasma Injections for the Treatment of Female Sexual Dysfunction and Stress Urinary Incontinence: A Systematic Review

Use of injection methods in genitourinary syndrome of menopause

Contact Info

Product

Resources

About