Background
Little is known about patterns of medication use and lifestyle counseling in patients with peripheral artery disease (PAD) in the United States.
Objective
We sought to evaluate trends in both medical therapy and lifestyle counseling for PAD patients in the United States from 2005 through 2012.
Methods
Data from 1,982 outpatient visits among patients with PAD were obtained from the National Ambulatory Medical Care Survey and National Hospital Ambulatory Medical Care Survey, a nationally representative assessment of office-based and hospital outpatient department practice. We evaluated trends in the proportion of visits with medication use (antiplatelet therapy, statins, ACE-inhibitors [ACE-I] or angiotensin receptor blockers [ARB], and cilostazol) and lifestyle counseling (exercise or diet counseling and smoking cessation).
Results
Over the 8-year period, the average annual number of ambulatory visits in the U.S. for PAD was 3,883,665. Across all visits, mean age was 69.2 years, 51.8% were female and 56.6% were Non-Hispanic white. Comorbid coronary artery disease (CAD) was present in 24.3% of visits. Medication use for cardiovascular prevention and symptoms of claudication was low: any antiplatelet therapy in 35.7% (standard error [SE] 2.7), statin 33.1% (SE, 2.4), ACE-I/ARB 28.4% (SE, 2.0), and cilostazol in 4.7% (SE, 1.0) of visits. Exercise or diet counseling was used in 22% (SE, 2.3) of visits. Among current smokers with PAD, smoking cessation counseling or medication was used in 35.8% (SE, 4.6) of visits. There was no significant change in medication use or lifestyle counseling over time. Compared to visits for patients with PAD alone, comorbid PAD and CAD were more likely to be prescribed antiplatelet therapy (OR 2.6 [1.8–3.9]), statins (OR 2.6 [1.8–3.9]), ACE-I/ARB (OR 2.6 [1.8–3.9]), and smoking cessation counseling (OR 4.4 [2.0–9.6]).
Conclusions
The use of guideline-recommended therapies in patients with PAD was much lower than expected, which highlights an opportunity to improve the quality of care in these high-risk patients.