Use of Probiotics as a Prophylaxis for Hepatic Encephalopathy: A Review Article

Salehi, Farzan; Singla, Jennis; Nasir, Asma; Nazary, Kefayatullah; Bassi, Gurnoor Singh; Maldonado, Jennifer Alicea; Gupta, Akash; Zubair, Maryam; Proano, Relfa Dellanira; Goraya, Simran; Bermudez-Wallman, Edith; Vaughan, Wilson Olaotan; Khudayar, Muhammad; Shah, Rutul; Krishnamoorthy, Sangeetha

doi:10.26502/aimr.0059

Cited by 1 publication

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This may promote the translocation of bacteria and systemic inflammation. 1 Probiotics able to modify gut flora when ingested in adequate amounts. Probiotics may alter these imbalance by reduce the amount of pathogenic bacteria and alter…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Benefit of probiotics in preventing hepatic encephalopathy among patients with liver cirrhosis: an evidence-based case report

Prabundari¹

2022

Udayana In. Med.

View full text Add to dashboard Cite

Background: Hepatic encephalopathy (HE) is a serious complication in patients with liver cirrhosis. Its pathogenesis involved the mechanism of HE including endotoxins, ammonia production and other neurotoxins by gut microflora. Probiotic exert potential benefit for gastrointestinal microflora. The use of probiotics may provide substantial benefit for the treatment of HE. Objective: This report aimed to evaluate the benefit of probiotics in preventing HE among liver cirrhosis patients. Methods: Literature searching with keywords of ‘liver cirrhosis’, ‘probiotics’, ‘hepatic encephalopathy’ along with its synonyms and related terms was implemented in Pubmed. Additional hand-search was implemented to obtain the relevant articles Result: Three meta-analyses showed that probiotics are effective to prevent HE development. All meta-analyses obtained similar results, in which the odds ratio (OR) obtained was ranging from 0.22 to 0.42. One randomized controlled trial (RCT) by Dhiman et al showed that probiotics treatment reduces the relative risk of overt HE by 33% compared to placebo. Conclusion: Probiotics administration exert potential to prevent the development of HE in the liver cirrhotic patients. The patient may benefit with the given of probiotics.

show abstract

Section: Discussionmentioning

confidence: 99%

“…It could range from mild alteration in level of consciousness to coma. 1 Overt HE estimated to occur in approximately 30% to 45% of cirrhosis patients. 2 A study by Bustamante et al 3 found that the survival probability at 1 and 3 years of monitoring of the patient after the first episode of HE was 42% and 23%, respectively.…”

Section: Introductionmentioning

confidence: 99%

Benefit of probiotics in preventing hepatic encephalopathy among patients with liver cirrhosis: an evidence-based case report

Prabundari¹

2022

Udayana In. Med.

View full text Add to dashboard Cite

show abstract

Use of Probiotics as a Prophylaxis for Hepatic Encephalopathy: A Review Article

Cited by 1 publication

References 0 publications

Benefit of probiotics in preventing hepatic encephalopathy among patients with liver cirrhosis: an evidence-based case report

Benefit of probiotics in preventing hepatic encephalopathy among patients with liver cirrhosis: an evidence-based case report

Contact Info

Product

Resources

About