Use of prolactin as an indicator of stress in Marwari sheep from arid tracts in India

Kataria, N.; Kataria, A. K.

doi:10.1007/s00580-010-0998-1

Cited by 8 publications

(5 citation statements)

References 18 publications

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“…This indicates that elevated prolactin could support thermoregulation at high environmental temperatures (Alamer, 2011). Further explanation can be provided by the findings of Kataria and Kataria (2011), who found a nearly 5-fold rise in plasma prolactin concentration associated with stress that originated from different pathologies such as Haemonchus contortus infestation, pneumonia, and enterotoxaemia in Marwari sheep. These stress responses can explain the increase in plasma prolactin during HS (P2 and P3) and the lower plasma prolactin concentrations in wethers fed CD.…”

Section: Effect Of Grain Type On Feed and Water Intakementioning

confidence: 89%

Reducing rumen starch fermentation of wheat with three percent sodium hydroxide has the potential to ameliorate the effect of heat stress in grain-fed wethers1,2

Gonzalez-Rivas

DiGiacomo

Giraldo

et al. 2017

Journal of Animal Science

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Selection for high productivity has resulted in ruminants adversely affected by heat stress (HS) due to their high metabolic rate and feed intake. One mechanism to ameliorate HS is to reduce the forage-to-concentrate ratio in the diet, although the inclusion of readily fermentable grains can reduce heat tolerance. The aim of these experiments was to investigate a chemical method for reducing the rate of fermentation of wheat and its effect on improving heat tolerance in sheep. In the first experiment, fermentation kinetics and buffered rumen fluid pH variation during in vitro incubation of corn, wheat, and 3% NaOH-treated wheat grains were compared. This experiment showed that corn and 3% NaOH-treated wheat had a slower (-23 and -22%, respectively; < 0.001) rate of gas production and elevated buffered rumen fluid pH ( < 0.001) compared with wheat. In the second experiment, 31 Merino × Poll Dorset wethers were housed in 2 climate-controlled rooms and were fed either corn grain plus forage (42.7% starch; were fed either corn grain plus forage (CD), wheat grain plus forage (WD) or 3 % NaOH-treated wheat plus forage (TWD) during 3 experimental periods: period 1 (P1), which consisted of 7 d of thermoneutral conditions (18 to 21°C and 40 to 50% relative humidity) and 1.7 times maintenance feed intake; period 2 (P2), which consisted of 7 d of HS (28 to 38°C and 30 to 50% relative humidity) and the same feed intake as in P1; and period 3 (P3), which consisted of 7 d of HS as in P2 and 2 times maintenance feed intake in a randomized control experiment. Water was offered ad libitum. The impact of HS was quantified by increases in rectal temperature, respiration rate (RR), and flank skin temperature (FT); variations in blood acid-base balance; and glucose, NEFA, and heat shock protein 70 (HSP-70) plasma concentrations. All physiological variables were elevated during HS, especially when wethers had greater feed intake (P3). Wethers fed CD had lower RR, rectal temperature, and FT than wethers fed WD ( < 0.001) and wethers fed TWD had lower RR and FT than wethers fed WD during HS ( < 0.05). There were reductions in blood CO, HCO3, and base excess concurrent with increases in blood partial pressure of O and pH during HS ( < 0.05). Heat stress reduced plasma NEFA and glucose concentrations whereas it increased prolactin ( < 0.05). Prolactin and HSP-70 plasma concentrations were greater for WD-fed wethers ( < 0.001) associated with Prolactin and HSP-70 plasma concentrations were greater for WD fed wethers (P < 0.001) during HS. These data indicate that the slow rate of rumen fermentation of CD and TWD can reduce the heat released during feed fermentation in the rumen, improving heat tolerance in sheep.

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Section: Effect Of Grain Type On Feed and Water Intakementioning

confidence: 89%

Reducing rumen starch fermentation of wheat with three percent sodium hydroxide has the potential to ameliorate the effect of heat stress in grain-fed wethers1,2

Gonzalez-Rivas

DiGiacomo

Giraldo

et al. 2017

Journal of Animal Science

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“…Looking at the relationships between the investigated parameters, serum prolactin values were not correlated with stress score and they were weakly negatively correlated with serum cortisol levels. Several authors have reported that stressful situations can lead to higher circulating prolactin levels in various species [3,4,5,6,7,8,9,11,12,13,14,15,16], suggesting that prolactin might be a good biomarker of acute stress. Results of the current study seem not to support this hypothesis.…”

Section: Discussionmentioning

confidence: 99%

“…In fact, the important genetic role of the prolactin receptor (PRL-R) in energy balance and metabolic adaptation has been recently evidenced in rodents, proving that prolactin has essential roles for the metabolism of glucose, insulin and lipids, as well as in promoting a positive energy balance [2]. Furthermore, prolactin has been found to be an index of acute stress in some non-human animal species, such as rats [3,4,5], domestic ruminants [6], donkeys [7], cattle [8], and sheep [9]; and different specific functions of prolactin during the stress response have also been demonstrated [2], such as mediation in the epidermal adaptation to environmental stress in fish [10].…”

Section: Introductionmentioning

confidence: 99%

Investigating the Role of Prolactin as a Potential Biomarker of Stress in Castrated Male Domestic Dogs

Gutiérrez

Gazzano

Pirrone

et al. 2019

Animals

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Simple SummaryAlthough cortisol is usually considered the main reference for the assessment of stress, in some animal species it has been shown that prolactin can be used as a biomarker of both acute and chronic stress. Behavioural parameters can also be used to assess the state of welfare and stress. This study was aimed at evaluating the possible relationship between serum prolactin, serum cortisol and behavioural signs of stress in domestic dogs. To reduce the possible influence of some factors, the study was performed on a homogeneous sample formed by 40 castrated male Spanish Greyhound dogs housed in a dog shelter. The weak negative correlation found between serum cortisol and prolactin values agrees with results obtained in other studies, indicating that prolactin response might be an alternative to cortisol response.AbstractProlactin has been recently regarded as a potential biomarker of both acute and chronic stress in several species. Since only few studies until now have focussed on domestic dogs, this study was aimed at evaluating whether prolactin, cortisol and stress behaviour correlated with each other in sheltered dogs. Both cortisol and prolactin analysis were performed in serum samples through a hormone-specific ELISA kit. For each dog, a stress score was calculated by summing the number of occurrences of stress-related behaviours. The presence/absence of fear during the time spent in the collection room was also scored for each individual. Results revealed a weak negative correlation between cortisol and prolactin levels. Neither of the hormones was correlated with the stress score, nor did their values seem to be influenced by showing fear in the collection room. The weak negative correlation found between cortisol and prolactin values agrees with results obtained in other studies, indicating that prolactin response might be an alternative to cortisol response. This, together with the high serum prolactin levels compared to those reported by other authors for healthy domestic dogs, may indicate that prolactin might be a good biomarker of chronic stress, and although further studies are needed to better understand the potential role of prolactin in the evaluation of canine welfare.

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“…Prolactin (PRL) is a polypeptide neurohormone that plays multiple homeostatic roles in the organism in conjunction with the dopaminergic system [ 12 ]. PRL blood levels increase during acute or chronic stress (due to psychological or physiological stressors) and increased levels of PRL have been linked to emotional disorders and anxiety-related behaviors in several mammalian species [ 13 , 14 , 15 ]. PRL may change in response to psychological stress also in humans, where different studies have shown a positive correlation between anxiety and negative emotions and serum PRL [ 16 , 17 , 18 ].…”

Section: Introductionmentioning

confidence: 99%

Neurohormonal Profiles of Assistance Dogs Compared to Pet Dogs: What Is the Impact of Different Lifestyles?

Mengoli

Oliva

Mendonça

et al. 2021

Animals

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Assistance dogs must manage stress efficiently because they are involved in challenging tasks. Their welfare is currently a fundamental issue. This preliminary study aimed to compare assistance dogs (AD; n = 22) with pet dogs (PD; n = 24), using blood neuromodulator indicators to help find biomarkers that can improve the AD breeding, selection, training, and welfare monitoring. Both populations originated from different breeds, are of different ages, and had different lifestyles. Basal peripheral concentrations of prolactin (PRL), serotonin (5-HT), free (fOT) and total (tOT) oxytocin were measured by immunoassays. Multiple linear regressions were performed to assess the effect of activity, age, sex, and their interactions on these parameters. Correlations between neurohormonal levels were analyzed. No interactions were significant. fOT and tOT concentrations were significantly influenced by age (p < 0.0001 and p = 0.0002, respectively) and dogs’ activity (p = 0.0006 and p = 0.0277, respectively). A tendency was observed for age effect on PRL (p = 0.0625) and 5-HT (p = 0.0548), as well as for sex effect on tOT (p = 0.0588). PRL concentrations were heterogenous among AD. fOT and tOT were significantly but weakly correlated (Pearson’s r = 0.34; p = 0.04). Blood prolactin, serotonin, and oxytocin may represent biomarkers to assess workload and chronic stress-related responses in ADs and eventually improve their selection and training.

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Use of prolactin as an indicator of stress in Marwari sheep from arid tracts in India

Cited by 8 publications

References 18 publications

Reducing rumen starch fermentation of wheat with three percent sodium hydroxide has the potential to ameliorate the effect of heat stress in grain-fed wethers1,2

Reducing rumen starch fermentation of wheat with three percent sodium hydroxide has the potential to ameliorate the effect of heat stress in grain-fed wethers1,2

Investigating the Role of Prolactin as a Potential Biomarker of Stress in Castrated Male Domestic Dogs

Neurohormonal Profiles of Assistance Dogs Compared to Pet Dogs: What Is the Impact of Different Lifestyles?

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