2021
DOI: 10.1177/1078155221995230
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Use of sublingual tacrolimus in adults undergoing hematopoietic cell transplant: A pilot study

Abstract: Introduction Orally administered tacrolimus is widely used in hematopoietic cell transplant patients, but multiple clinical situations may arise rendering oral administration infeasible. The undesirable sequelae of intravenous administration, including toxicity, challenges with administration and cost call for innovative solutions to conserve existing supply and optimize safety and efficacy of medication delivery. We sought to demonstrate feasibility of sublingual tacrolimus use and estimate a sublingual-to-or… Show more

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