ammography and ultrasound are common anatomical imaging procedures used to detect breast cancer. While screening mammography, especially when combined with ultrasound, has demonstrated the ability to detect non-palpable breast cancer, these modalities still suffer from some significant limitations. According to the results of the American College of Radiology Imaging Network (ARCIN) 6666 clinical trial, the combination of mammography and ultrasound resulted in a positive predictive value of only 11.2% and a missed breast cancer in 8 of the 40 (sensitivity 80%) participants with malignant lesions. 1 In recent years, molecular imaging technologies have been developed to address these limitations.