Use of the newer autonomic blocking agents in the study and treatment of peripheral vascular disease

Action of Dibenyline on the Peripheral Circulation

“…Studies with dibenyline in patients with peripheral vascular disease have yielded conflicting results. Moser et al (1953), Haimovici (1951, Friend and Edwards (1954), and Wertheimer et al (1954) found it valuable when given intravenously or orally in the treatment of vasospastic disorders, causalgia, and acrocyanosis. Wertheimer et al (1954) claimed some benefit in arteriosclerosis obliterans, but most workers consider the drug to be less efficacious in organic vascular disorders.…”