Use of the Recanalised Umbilical Vein for Islet Autotransplantation following Total Pancreatectomy

Embolization of percutaneous transhepatic portal venous access tract withN-butyl cyanoacrylate

“…[7][8][9][22][23][24][25] Among these routes, TIPS and percutaneous transhepatic access are the two most commonly used access routes. Compared with the TIPS access, the percutaneous transhepatic access offers direct access to the portal vein along the long axis of the portal vein and allows easier access to the peripheral intrahepatic portal vein branches.…”

“…28,29 Various materials are used for embolization of tracts in the liver parenchyma after portal vein manipulation, including gelatin sponge particles, biological tissue adhesives, coils and vascular plugs. [10][11][12][13][23][24][25] The most commonly used embolic materials for the closure of percutaneous portal vein access tracts are coils and gelatin sponge particles; however, they have their own drawbacks. With the use of gelatin sponge particles, incomplete tract embolization or delayed bleeding may occur owing to its soluble and impermanent nature.…”

Strategies in Preventing Diabetes after Pancreatectomy Using Islet Auto- and Allo-Transplantation

“…The results showed that the umbilical vein approach had no significant difference of postoperative metabolic function compared to non-umbilical vein approaches [59].…”

“…One benefit of umbilical vein as a route for islet transplant is the possibility to monitor pressure of the portal vein for up to 5-days post transplantation [59]. patient received sufficient dose of islets and maintained the transplanted islet survival.…”

Total Pancreatectomy and Islet Autotransplantation for Chronic Pancreatitis

“…However, techniques also exist for intraportal embolizaiont of islet so the liver after abdominal closure has been obtained. The techniques include emoblization to a temporarily exteriorized omental vein (Nath et al, 2004); via a recanalized umbilical vein (Pollard et al, 2011) or percutaneous transhepatic access to the portal vein for infusion of the islets (Morgan et al, 2011). The latter approach frees up surgeons and an operating room for other procedures sooner than if the islets are infused in the operating room and thus is thought to be cost-effective at least at one center (Morgan et al, 2011), but the expense incurred by using interventional radiology must also be considered as well as the fact that the abdomen cannot be inspected for bleeding after the heparinization and increased portal pressure that ensue by lieu of the infusion (Blondet et al, 2007).…”