Use of Tris(2-carboxyethyl)phosphine for Quantitation of Iodine and Iodate

Tris(2-carboxyethyl)phosphine Hydrochloride

“…TCEP and the DTNB/NTB system have also been used as an analytical tool for the quantification of sulfides, disulfides, hypochlorous acid, hypochlorite ions, iodine, iodate ions, hydrogen peroxide, ascorbic acid, and dehydroascorbic acid. [33][34][35][36][37] Macrocyclic peptide synthesis via thia zip cyclization 38 involving a series of intramolecular rearrangements in a cysteine-rich peptide has been facilitated using TCEP to prevent disulfide formation. TCEP has also been used to facilitate the conjugation of peptides to oligonucleotides by native chemical ligation.…”

Spectrophotometric Assay for Hypochlorite/Hypochlorous Acid Using Tris(2-carboxyethyl)phosphine

“…This reducing agent has been previously employed for quantitation of H 2 O 2 , iodine, and iodate (11,12). In this study, we demonstrated that TCEP can also be effectively used for quantitation of HOCl/OCl 0 .…”

“…Recently, we reported the use of tris(2-carboxyethyl)phosphine (TCEP) for assay of hydrogen peroxide and iodine (11,12). In the present study, we employ TCEP for quantitative determination of OCl 0 or HOCl.…”