“…A number of techniques capable of early detection have been proposed, including the ultrasonic visualisation of subcutaneous oedema [4, 7, 8]. High frequency ultrasound (HFUS), at a frequency of 20 MHz, allows the real-time two-dimensional imaging of internal structures in a noninvasive manner and has been shown to be a potentially valuable method for the assessment of subcutaneous tissue damage pertaining to numerous pathophysiologies including the evaluation of wounds [7, 9–11]. The potential it offers in establishing parameters associated with the echogenicity of the ultrasound image could provide earlier identification of tissue damage than that being achievable through clinical skin assessment or photography alone [7, 8].…”