Use of vibrational optical coherence tomography to measure viscoelastic properties of muscle and tendon: A new method to follow musculoskeletal injury and pathology In vivo

Silver, Frederick H.; Kelkar, Nikita; Deshmukh, Tanmay

doi:10.1016/j.jmbbm.2021.104479

Cited by 1 publication

(1 citation statement)

References 22 publications

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“…As can be seen in the aforementioned examples, quasi-static compression OCE, mostly phase-sensitive with some sort of compliance layer as stress sensor, is currently the most advanced OCE method. In the last few years, other approaches rose to the horizon of feasibility, e.g., vibrational OCE, 311,312 which uses OCT to record the reaction of a sample to a variation of vibration frequencies. With this, a 3D resonant frequency map of the sample can be generated and viscoelastic behavior can be investigated.…”

Section: Optical Coherence Elastography: Depth Resolved Optical Palpationmentioning

confidence: 99%

Enhanced medical diagnosis for dOCTors: a perspective of optical coherence tomography

et al. 2021

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Significance: After three decades, more than 75,000 publications, tens of companies being involved in its commercialization, and a global market perspective of about USD 1.5 billion in 2023, optical coherence tomography (OCT) has become one of the fastest successfully translated imaging techniques with substantial clinical and economic impacts and acceptance.Aim: Our perspective focuses on disruptive forward-looking innovations and key technologies to further boost OCT performance and therefore enable significantly enhanced medical diagnosis.Approach: A comprehensive review of state-of-the-art accomplishments in OCT has been performed. Results:The most disruptive future OCT innovations include imaging resolution and speed (single-beam raster scanning versus parallelization) improvement, new implementations for dual modality or even multimodality systems, and using endogenous or exogenous contrast in these hybrid OCT systems targeting molecular and metabolic imaging. Aside from OCT angiography, no other functional or contrast enhancing OCT extension has accomplished comparable clinical and commercial impacts. Some more recently developed extensions, e.g., optical coherence elastography, dynamic contrast OCT, optoretinography, and artificial intelligence enhanced OCT are also considered with high potential for the future. In addition, OCT miniaturization for portable, compact, handheld, and/or cost-effective capsule-based OCT applications, home-OCT, and self-OCT systems based on micro-optic assemblies or photonic integrated circuits will revolutionize new applications and availability in the near future. Finally, clinical translation of OCT including medical device regulatory challenges will continue to be absolutely essential.Conclusions: With its exquisite non-invasive, micrometer resolution depth sectioning capability, OCT has especially revolutionized ophthalmic diagnosis and hence is the fastest adopted imaging technology in the history of ophthalmology. Nonetheless, OCT has not been completely exploited and has substantial growth potential-in academics as well as in industry. This applies not only to the ophthalmic application field, but also especially to the original motivation of OCT to enable optical biopsy, i.e., the in situ imaging of tissue microstructure with a resolution approaching that of histology but without the need for tissue excision.

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Section: Optical Coherence Elastography: Depth Resolved Optical Palpationmentioning

confidence: 99%

Enhanced medical diagnosis for dOCTors: a perspective of optical coherence tomography

et al. 2021

View full text Add to dashboard Cite

show abstract

Use of vibrational optical coherence tomography to measure viscoelastic properties of muscle and tendon: A new method to follow musculoskeletal injury and pathology In vivo

Cited by 1 publication

References 22 publications

Enhanced medical diagnosis for dOCTors: a perspective of optical coherence tomography

Enhanced medical diagnosis for dOCTors: a perspective of optical coherence tomography

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