Use of Vitamin D In Critically ill Covid-19 Patients  Kritik Covid-19 Hastalarında D Vitamini Kullanımı

Sahar, İsa; Şenoğlu, Nimet; Rollas, Kazım; Çalışkan, Taner; Güldoğan, Işıl Köse; Zinciroğlu, Çiler; Sarıtaş, Aykut; Uzun, Uğur

doi:10.17932/iau.asd.2015.007/asd_v08i2002

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“…Scholarly views have been also expressed that this may be related to an enzyme defect or lack of intestinal absorption in the Turkish population ( 39 ). There are studies from two other cities, namely Izmir and Canakkale, in Turkey which investigated whether vitamin D levels are associated with the need for mechanical ventilation, ICU admission and length of stay, hospitalization, and COVID-19 related in-hospital mortality in critically ill COVID-19 patients ( 40 , 41 ). It is thus important, to emphasize the importance of regional studies.…”

Section: Discussionmentioning

confidence: 99%

Shedding light on the next pandemic path, from outpatient to ICU, the effect of vitamin D deficiency in the SARS-CoV-2 pandemic

Celikmen,

Tunaligil,

Keles

et al. 2024

Front. Nutr.

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BackgroundVitamin D insufficiency is named “the pandemic of our era” by some experts. World Health Organization warns against a “deadlier outbreak” than the COVID-19 pandemic. Critical evidence is hereby for future pandemic prevention, with special emphasis on Vitamin D.MethodsA cross-sectional study was conducted with 172 unvaccinated adult participants, who presented to the emergency department. Blood measurements, radiological findings, and demographic features were evaluated in the four categories of “healthy adults, COVID-19 outpatients, hospitalized inpatients on the wards, and in the ICU.”ResultsResults were statistically significant in association with age, gender, weight, Vitamin D, glucose, urea, creatinine, leucocyte, aspartate transaminase, hemoglobin, C-reactive protein, troponin, platelet/thrombocyte, ferritin, D-dimer, triglycerate, glycated haemoglobin, lactate dehydrogenase measurements, and chest computed tomography features (each p < 0.050).ConclusionThis article presents evidence to support the importance of Vitamin D for global public health. Patients with adequate levels of Vitamin D, glucose, urea, creatinine, leucocyte, aspartate transaminase, hemoglobin, C-reactive protein, troponin, platelet/thrombocyte, ferritin, D-dimer, triglycerate, glycated haemoglobin, lactate dehydrogenase are less likely to be admitted to ICU versus being outpatients. Factors include gender, age, weight, comorbidities, and computed tomography findings. The ultimate goal is to globally minimize preventable burdens of disease and death.

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Section: Discussionmentioning

confidence: 99%