The results of a calculation of the neutron-physical characteristics of different variants of the fuel load of a VVER-1000 core are presented. The load completely consists of either enriched natural uranium (standard fuel) or recovered fuel, consisting of a uranium-plutonium mixture of recovered material, recovered plutonium, and highly enriched uranium. The mass fraction of plutonium isotopes in the recovered fuel ranged from 2 to 5%. All load variants examined have the same energy potential. The neutron-physical characteristics of a core with a full load of uranium are compared for a core with recovered uranium-plutonium fuel. Analysis of the neutron-physical characteristics did not show any fundamental limitations on the possibility of a VVER-1000 core load consisting entirely of recovered uranium-plutonium fuel.It is proposed in [1] that fuel based on recovered uranium-plutonium (an unseparated mixture of isotopes) which is separated from the spent fuel from thermal reactors and from which other actinides and fission products are removed and is mixed (taking account of the compensation and even isotopes of uranium and plutonium) with enriched natural uranium be used in thermal reactors. The specific consumption of natural uranium in the production of such fuel is approximately 20% lower than for fabrication of uranium fuel, and the specific separation work required to enrich the uranium part of the mixture remains almost unchanged [2]. The neutron-physical characteristics of a core with a 100% load of uranium and recovered uranium-plutonium fuel which affect the VVER-1000 operating safety differed negligibly, since the mass fraction of plutonium in the recovered fuel is approximately 1% [2].The required content of fissile nuclides in the fuel can be obtained by adding to the reprocessed uranium-plutonium and mixture, together with enriched natural uranium, the plutonium separated from spent VVER-440 fuel. Many years of European experience has validated the possibility of using in PWR plutonium mixed with uranium-plutonium fuel (mixture of recovered plutonium and depleted uranium) with mass fraction of plutonium fissile isotopes 4-6% [3].