Usefulness of 3-Tesla Cardiac Magnetic Resonance to Detect Mitral Annular Disjunction in Patients With Mitral Valve Prolapse

Essayagh, Benjamin; Iacuzio, Laura; Civaia, Filippo; Avierinos, Jean-François; Tribouilloy, Christophe; Lévy, F.

doi:10.1016/j.amjcard.2019.08.047

Cited by 53 publications

(58 citation statements)

References 21 publications

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“…On echocardiography, this is most commonly seen in the parasternal long-axis view [9]. Studies focused on MAD, using CMR, confirmed that in patients with late gadolinium enhancement (LGE), presence of LV fibrosis at level of papillary muscle was more frequent in patient with MAD and, according to other studies, showed that patients with MAD have the tendency to be younger and with lower ejection fraction (LVEF), irrespectively of MR severity [10].…”

Section: Discussionmentioning

confidence: 84%

Mitral Annular Disjunction and Arrhythmic Risk: A Case Report

Pascariello¹,

Berlinghieri²,

Cimino³

et al. 2020

Preprint

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Mitral annular disjunction (MAD) is a structural abnormality of the mitral annulus, defined by a detachment of the atrial wall-mitral valvular junction from the left ventricular (LV) free wall. This structural abnormality in mitral annulus fibrosus is significantly associated with the presence of mitral valve prolapse (MVP) [1], but it can be also detected in normal cases as an anatomical variation of the mitral annulus fibrosus [2]. The main tools to detect MAD are echocardiography and cardiac magnetic resonance. Prevalence of MAD in the general population ranges from 7% [1] to 9% [2]. Several studies proved an association between MAD and arrhythmic events, independently of concomitant mitral valve abnormalities, suggesting the existence of a novel entity: MAD arrhythmic syndrome [3]. Herein we describe a case report of a middle age man with MAD who experienced ventricular arrhythmias and placement of an implantable cardioverter-defibrillator (ICD).

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Section: Discussionmentioning

confidence: 84%

Mitral Annular Disjunction and Arrhythmic Risk: A Case Report

Pascariello¹,

Berlinghieri²,

Cimino³

et al. 2020

Preprint

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“…Moreover, patients with FED can suffer from SCD but, differently from BD patients, SCD is likely due to arrhythmias related to severe MR, LV dilatation, and dysfunction [24]. Moreover, as reported by Mantegazza et al [18] and Essayagh et al [25], the prevalence of MAD is higher in patients with BD compared to those with FED. Unfortunately, at present, there are no studies comparing CMR features of fibrosis in FED versus BD patients (Figure 2).…”

Section: Definition Of Mitral Valve Prolapsementioning

confidence: 93%

Diagnosis of Mitral Valve Prolapse: Much More than Simple Prolapse. Multimodality Approach to Risk Stratification and Therapeutic Management

Alenazy

Eltayeb

Alotaibi

et al. 2022

JCM

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Mitral valve prolapse (MVP) is the most common valvular disease with a prevalence of 2%. It has generally a benign course; however, recent findings suggested an association between MVP and complex arrhythmias and eventually cardiac arrest and for this reason, it is also called arrhythmogenic MVP. Subjects who experience this complication are in general young women, with thickened mitral leaflets or bileaflet prolapse not necessarily associated with severe mitral regurgitation (MR). The nature of the relation between MVP and cardiac arrest is not clearly understood. Actually, the challenging task is to find the cluster of prognostic factors including T-wave inversion, polymorphic premature ventricular contractions, bileaflet prolapse, MR severity, but most importantly, those parameters of hypercontractility, mitral annulus disjunction (MAD), and myocardial fibrosis using a multimodality approach. Transthoracic echocardiography is the first-line imaging modality for the diagnosis of MVP, but also for detecting MAD and hypercontractility, followed by cardiac magnetic resonance for tissue characterization and detection of myocardial and papillary muscle fibrosis, using either late gadolinium enhancement (at the basal segment of the inferolateral wall and papillary muscles) (macro-fibrosis), or diffuse fibrosis by T1 mapping (native and post contrast T1). Moreover, there are also preliminary data on positron emission tomography utilizing 18F-fluorodeoxyglucose as a tool for providing evidence of early myocardial inflammation. The objective of this review article is to provide the clinician with an overview and a practical clinical approach to MVP for risk stratification and treatment guidance.

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“…Puede proveer una evaluación precisa de la disfunción miocárdica, motilidad segmentaria, fibrosis o grado de severidad, y evaluar el diámetro telediastólico del VI, sobre todo en el contexto de remodelamiento esférico apical y medioventricular de dicha cámara (3,24) . Además, es superior a la ecocardiografía 2D y 3D para la caracterización de la disfunción del anillo mitral (25) .…”

Section: E Resonancia Magnética Nuclear (Rmn)unclassified

Actualización en insuficiencia mitral funcional: una revisión integral

Olivares

Carrasco-Rueda

Ocmin³

et al. 2020

APCyCCV

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Los avances en el manejo de la insuficiencia mitral (IM) funcional en las últimas décadas, hacen que el conocimiento de la misma sea de suma importancia para el cardiólogo clínico, al tener una prevalencia cada vez mayor en pacientes mayores de 50 años. Esta revisión tiene como objetivo dar a conocer de una manera integral las bases fisiopatológicas de la IM para diferenciar sus mecanismos, y correlacionarlos con los hallazgos clínicos, hemodinámicos y de imágenes que valoran la severidad de la enfermedad. Estos datos son relevantes para la adecuada selección del paciente y del momento oportuno de las intervenciones terapéuticas, lo cual involucra a un equipo multidisciplinario en la toma de decisiones para lograr el mayor beneficio dentro de las opciones de tratamiento de esta patología.

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Usefulness of 3-Tesla Cardiac Magnetic Resonance to Detect Mitral Annular Disjunction in Patients With Mitral Valve Prolapse

Cited by 53 publications

References 21 publications

Mitral Annular Disjunction and Arrhythmic Risk: A Case Report

Mitral Annular Disjunction and Arrhythmic Risk: A Case Report

Diagnosis of Mitral Valve Prolapse: Much More than Simple Prolapse. Multimodality Approach to Risk Stratification and Therapeutic Management

Actualización en insuficiencia mitral funcional: una revisión integral

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