2009
DOI: 10.1016/j.amjcard.2009.01.024
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Usefulness of a Combination of Systolic Function by Left Ventricular Ejection Fraction and Diastolic Function by E/E′ to Predict Prognosis in Patients With Heart Failure

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Cited by 54 publications
(56 citation statements)
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“…At discharge, higher left ventricular fi lling pressures are an accurate predictor of repeat hospitalization and increased mortality [25,26]. While the overall accuracy of E/e' for prediction of diastolic fi lling pressure remains the subject of intense debate [27,28], our results agree with fi ndings from several recent studies examining the relation between elevated E/e' at discharge and increased readmission rates [29,30]. Thus, E/e' also might provide a ready measure of response to treatment and a useful noninvasive marker for elevated fi lling pressures, especially in patients with HFNEF.…”
Section: Discussionsupporting
confidence: 82%
“…At discharge, higher left ventricular fi lling pressures are an accurate predictor of repeat hospitalization and increased mortality [25,26]. While the overall accuracy of E/e' for prediction of diastolic fi lling pressure remains the subject of intense debate [27,28], our results agree with fi ndings from several recent studies examining the relation between elevated E/e' at discharge and increased readmission rates [29,30]. Thus, E/e' also might provide a ready measure of response to treatment and a useful noninvasive marker for elevated fi lling pressures, especially in patients with HFNEF.…”
Section: Discussionsupporting
confidence: 82%
“…For variables retained in the multivariate regression, hazard ratios were generated using optimal dichotomous threshold values. Previously established dichotomous threshold values for TAPSE, PASP, and E/e' measurements were used for survival analysis in the present study (22). Since TAPSE-to-PASP ratio (TAPSE/PASP) has not previously been assessed for prognostic value, a receiver operating characteristic (ROC) curve analysis was used to identify the optimal dichotomous threshold value.…”
Section: Patientsmentioning
confidence: 99%
“…The tissue Doppler imaging (TDI) of the mitral annulus movement was obtained from the apical four-chamber view. A 1.5-mm sample volume was placed sequentially at the lateral and septal annular sites, and the derived variables were averaged (22). Analysis was performed for the systolic (S') and the early (e') and late (a=) diastolic peak velocities.…”
Section: Patientsmentioning
confidence: 99%
“…This study demonstrated that 20% (65/310) of the patients developed an elevated E/E 0 C15 only after the exercise. While elevated resting E/E 0 C15 has been shown to provide prognostic information in patients with a wide range of cardiac diseases [22][23][24], the prognostic implications of isolated elevated post-exercise E/E 0 remain to be defined. Recently, Holland et al reported that raised exercise E/E 0 [ 14.5 is associated with cardiovascular hospitalization, independent of and incremental to inducible ischemia [25].…”
Section: Discussionmentioning
confidence: 99%