Usefulness of applying lidocaine in esophagogastroduodenoscopy performed under sedation with propofol

Morena, Felipe de la; Santander, Cecilio; Esteban, Carlos; Cuenca, B. de; García, Juan Antonio; Sánchez, Javier Jiménez; Moreno, Ricardo

doi:10.4253/wjge.v5.i5.231

Cited by 17 publications

(9 citation statements)

References 19 publications

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“…These findings compare favourably with those of prior studies by Sethi et al . and de la Morena et al . Sethi et al .…”

Section: Discussionmentioning

confidence: 94%

See 1 more Smart Citation

A comparison of propofol vs. dexmedetomidine for sedation, haemodynamic control and satisfaction, during esophagogastroduodenoscopy under conscious sedation

Zhang

et al. 2015

J Clin Pharm Ther

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“…These findings compare favourably with those of prior studies by Sethi et al . and de la Morena et al . Sethi et al .…”

Section: Discussionmentioning

confidence: 94%

“…demonstrated that dexmedetomidine was a superior alternative to midazolam for conscious sedation in endoscopic retrograde cholangiopancreatography (ERCP). In the study of de la Morena et al ,. the same dose of propofol provided moderate sedation, which was defined as a score of 3 on the OAA/S during the EGD procedure.…”

Section: Discussionmentioning

confidence: 98%

A comparison of propofol vs. dexmedetomidine for sedation, haemodynamic control and satisfaction, during esophagogastroduodenoscopy under conscious sedation

Zhang

et al. 2015

J Clin Pharm Ther

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“…Thus, topical lidocaine pharyngeal anesthesia is a routine procedure, which gives the advantage of lubrication and less discomfort 17 . For patients who undergo esophagogastroduodenoscopy under propofol sedation, whether topical pharyngeal anesthesia is needed remains a controversial topic 18 . Additionally, the current guidelines on sedated endoscopy did not make any suggestions on this topic, which should be further examined in clinical research 8 .…”

Section: Discussionmentioning

confidence: 99%

Topical pharyngeal anesthesia provides no additional benefit to propofol sedation for esophagogastroduodenoscopy: a randomized controlled double-blinded clinical trial

Sun

Zhang

et al. 2018

Sci Rep

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Propofol sedation has been applied during esophagogastroduodenoscopy procedures, but whether topical pharyngeal anesthesia should be administered at the same time has rarely been reported. Our study examined the role of topical pharyngeal anesthesia in sedated endoscopies in a randomized controlled double-blinded clinical trial. A total of 626 patients who underwent sedated esophagogastroduodenoscopy were randomized into the experimental group (n = 313) or the control group (n = 313). The discomfort score, immediately and one day after the procedure, was not statistically significant [7.2 (5–9) vs. 7.5 (6–9), P = 0.210; 2.3 (0–3) vs. 2.6 (0–4), P = 0.095, respectively]. Two patients in the experimental group and three patients in the control group needed oral medication for pharyngeal discomfort (P = 0.354). The satisfaction score was 9.2 (8–10) in the experimental group and 8.9 (7–10) in the control group (P = 0.778). Lidocaine topical pharyngeal anesthesia in propofol-sedated esophagogastroduodenoscopy did not further reduce the pharyngeal discomfort or improve the satisfaction. This clinical trial was registered at ClinicalTrials.gov (ClinicalTrials.gov ID: NCT03070379).

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“…[1][2][3][4] EGD can be performed in association with topical anesthesia of the pharynx, 5,6 intravenous anesthesia, [7][8][9] or with their combination. [10][11][12][13] EGD under topical pharyngeal anesthesia has the advantage of avoiding unwanted cardiopulmonary adverse events from intravenous sedationlike respiratory depression, cardiorespiratory arrest, especially in patients with cardiopulmonary disease, the elderly, and obese. [14][15][16] In Thailand, lidocaine spray is commonly used and is safe and easy in procedures requiring unsedated EGD.…”

Section: Introductionmentioning

confidence: 99%

Comparison of Lidocaine Spray and Lidocaine Ice Popsicle in Patients Undergoing Unsedated Esophagogastroduodenoscopy: A Single Center Prospective Randomized Controlled Trial

Mahawongkajit¹,

Talalak²,

Soonthornkes³

2021

CEG

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Purpose: Esophagogastroduodenoscopy (EGD) under topical pharyngeal anesthesia has the advantage of avoiding the unwanted cardiopulmonary adverse events experienced following intravenous sedation. Lidocaine spray is a common anesthetic option and is safe for unsedated EGD. Although several studies have compared different topical anesthetic agents, their formulations, and delivery techniques, questions still remain concerning the optimal mode of administration. We have designed a lidocaine formulation in the form of an ice popsicle and compared its effectiveness and tolerability with lidocaine spray in patients undergoing unsedated EGD. Methods: This was a single-center prospective randomized controlled trial. Unsedated EGD patients were randomly allocated the lidocaine spray [Group (Gp) A] or lidocaine ice popsicle (Gp B) formulation. Results: In total, 204 unsedated EGD patients were evaluated. Compared to the spray, the lidocaine ice popsicle group showed better scores for effects in terms of endoscopist satisfaction (Gp A, 7.28±1.

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Usefulness of applying lidocaine in esophagogastroduodenoscopy performed under sedation with propofol

Abstract: Topical pharyngeal anaesthesia is safe in EGD but does not reduce the necessary dose of propofol or improve the anaesthetist's or endoscopist's satisfaction with the procedure.

Cited by 17 publications

References 19 publications

A comparison of propofol vs. dexmedetomidine for sedation, haemodynamic control and satisfaction, during esophagogastroduodenoscopy under conscious sedation

A comparison of propofol vs. dexmedetomidine for sedation, haemodynamic control and satisfaction, during esophagogastroduodenoscopy under conscious sedation

Topical pharyngeal anesthesia provides no additional benefit to propofol sedation for esophagogastroduodenoscopy: a randomized controlled double-blinded clinical trial

Comparison of Lidocaine Spray and Lidocaine Ice Popsicle in Patients Undergoing Unsedated Esophagogastroduodenoscopy: A Single Center Prospective Randomized Controlled Trial

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