Usefulness of Atrial Fibrillation Burden as a Predictor for Success of Pulmonary Vein Isolation

Berkowitsch, Alexander; Greiß, Harald; Vukajlović, Dejan; Kuniss, Malte; Neumann, Thomas; Zaltsberg, Sergej; Kurzidim, Klaus; Hamm, Christian W.; Pitschner, Heinz F.

doi:10.1111/j.1540-8159.2005.00270.x

Cited by 40 publications

(46 citation statements)

References 23 publications

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“…The population that was studied in this research was relatively young (54.2 ± 9 years) and had not experienced significant symptoms of other co-morbid health conditions that may have had an impact on the SF-36 questionnaire results. The effect of the therapy that was applied on health-related QoL in patients with AF has been investigated in several studies [7,12,13], and these data are consistent with our findings.…”

Section: Qol Before and After Cpvasupporting

confidence: 82%

“…The results are consistent and describe a health-related improvement of the QoL in patients with highly symptomatic drug-resistant AF after CPVA [7,12,13]. Eighteen per cent of the patients had documented episodes of AF after CPVA (R group); however, their symptoms were limited.…”

Section: Qol Before and After Cpvasupporting

confidence: 67%

“…Results of the SF-36 questionnaire in patients who had a recurrence of atrial fibrillation after circumferential pulmonary vein ablation (CPVA); p < 0.05 for bodily pain (BP) and general health (GH); abbreviations as in Table 2 Data are expressed as the mean ± standard deviation and as median for abnormally distributed variables; NR -non-recurrence group; R -recurrence group; G -group, I -intervention (CPVA), GxI -interaction of the group and intervention; QoL -quality of life; other abbreviations as in Table 2 process or cardiac denervation, or may originate from the placebo effect. Further studies suggest that the improvement in QoL seems to be caused by changing previously symptomatic events into asymptomatic ones [12,13]; however, in our study we did not observe asymptomatic episodes of AF during Holter monitoring.…”

Section: Qol Before and After Cpvacontrasting

confidence: 52%

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Quality of life in patients with paroxysmal atrial fibrillation after circumferential pulmonary vein ablation

et al. 2016

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A b s t r a c tBackground: Atrial fibrillation (AF) is the most common arrhythmia and is associated with a deterioration of quality of life (QoL). Catheter ablation is a therapeutic strategy for some patients with AF. The effectiveness of pulmonary vein isolation is still under assessment. Aim:To assess the long-term influence of circumferential pulmonary vein ablation (CPVA) on QoL in patients with AF. Methods:The study population consisted of 33 patients (26 males, age 54.2 ± 9 years) with highly symptomatic (EHRA II-III) drug refractory paroxysmal AF, who underwent CPVA. A clinical examination, electrocardiogram (ECG), and Holter ECG were performed before and during a one-year follow-up. The SF-36 Medical Outcomes Survey Short-Form QoL questionnaire, scored on a 0-100 scale for each of eight domains: bodily pain (BP), general health (GH), mental health (MH), physical functioning (PF), role-emotional (RE), role-physical (RP), social functioning (SF), and vitality (V), was collected before and one year after CPVA. Results:In the one-year follow-up 27 (82%) patients were free of AF. EHRA symptoms were improved one-year after CPVA regardless of CPVA efficacy. After the follow-up the SF-36 questionnaire results improved significantly in all of the subscales in patients without a recurrence of AF after CPVA. In subjects with a recurrence of AF, all of the subscales did not indicate any statistically significant differences. There was an association between the CPVA and the following QoL domains: GH (p = 0.018), PF (p = 0.042), and V (p = 0.041). The highest values of the GH and V domains were found in the non-recurrence patients one year after CPVA. Conclusions:CPVA results in the clinical improvement of patients with symptomatic AF regardless of the final arrhythmia termination. Patients after successful CPVA experienced a significant improvement in all of the subscales of the QoL.

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Section: Qol Before and After Cpvasupporting

confidence: 82%

Section: Qol Before and After Cpvasupporting

confidence: 67%

Section: Qol Before and After Cpvacontrasting

confidence: 52%

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Quality of life in patients with paroxysmal atrial fibrillation after circumferential pulmonary vein ablation

et al. 2016

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“…Multiple single-center studies have shown substantial improvement in patients' quality of life after primary ablative intervention. [170][171][172] Several comparative studies found that quality of life after ablation is comparable with that of healthy persons not undergoing ablation.…”

Section: Success Ratesmentioning

confidence: 99%

Contemporary Management of Atrial Fibrillation: Update on Anticoagulation and Invasive Management Strategies

Crandall

Bradley

Packer

et al. 2009

Mayo Clinic Proceedings

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“…24 Patients with paroxysmal AF with >500 h in symptomatic AF within 3 months prior to admission were defined as "high burden" group and considered as non-paroxysmal AF (NPAF). 23 …”

Section: Af Burdenmentioning

confidence: 99%

Ipsilateral Circumferential Radiofrequency Ablation of Atrial Fibrillation With Irrigated Tip Catheter

Wójcik

Erkapic

Berkowitsch

et al. 2013

Circ J

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2280WÓJCIK M et al. We present a very long-term outcome and its predictors in a cohort of patients after single ipsilateral circumferential antrum pulmonary vein isolation (PVI) with irrigated tip catheter using uniform approach without 3-D mapping system at a single center. Methods Patient CharacteristicsTo determine long-term outcome, we retrospectively followed a cohort of 356 patients who had PVI performed at Kerckhoff trial fibrillation (AF) is the most common sustained clinical arrhythmia 1 associated with significant morbidity and impaired quality of life. 2,3 Medical therapy is of limited efficacy. 4,5 Catheter ablation of AF is an important therapeutic modality for patients with AF. 4-7The aim of catheter ablation for AF is to eliminate the triggers or substrate that initiate and maintain the disorder, to maintain sinus rhythm. 8 Findings from several multicenter prospective clinical trials, 9-11 systematic reviews, and metaanalyses 4,12-15 have consistently shown that catheter ablation is more effective than anti-arrhythmic drug (AAD) therapy for maintenance of sinus rhythm. 6 Furthermore, successful catheter ablation of AF was associated with improved symptoms and quality of life. 16, 17 The published data suggest that, although sinus rhythm is better preserved after ablation procedures than with AAD, late recurrences are not uncommon. 18 Despite the fact that the re-

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Usefulness of Atrial Fibrillation Burden as a Predictor for Success of Pulmonary Vein Isolation

Abstract: AF recurrence with AFB > or =12 hours within 3 months is associated with a missed improvement of QoL. Symptomatic ERAF predicts recurrence independently of therapy.

Cited by 40 publications

References 23 publications

Quality of life in patients with paroxysmal atrial fibrillation after circumferential pulmonary vein ablation

Quality of life in patients with paroxysmal atrial fibrillation after circumferential pulmonary vein ablation

Contemporary Management of Atrial Fibrillation: Update on Anticoagulation and Invasive Management Strategies

Ipsilateral Circumferential Radiofrequency Ablation of Atrial Fibrillation With Irrigated Tip Catheter

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