“…IgG4-related sclerosing cholangitis is frequently associated with autoimmune pancreatitis and is currently recognized as a biliary manifestation of IgG4 systemic disease [1]. The differential diagnosis from primary sclerosing cholangitis and cholangiocarcinoma is sometimes diffi-cult [2]. Peroral cholangioscopy has numerous applications in the diagnosis and treatment of various biliary disorders and can be a helpful diagnostic method to rule out malignancy in patients with IgG4-related sclerosing cholangitis [3].…”