“…However, large areas of scarring may also develop after myocarditis and mild to moderate regional dyssynergy is common in primary DCM. On the other hand, global left ventricular dysfunction occurs in patients with diffuse coronary disease (10). In the study of Vigna et al (11) the baseline hypocontractility tended to be less homogenous in patients with ischemic DCM than in those with nonischemic DCM, however large overlaps in the individual data were observed.…”
TDE parameters: early diastolic velocity, preejection period, isovolumic relaxation time and the dispersion index of systolic velocities differentiate ischemic and nonischemic etiology of dilated cardiomyopathy.
“…However, large areas of scarring may also develop after myocarditis and mild to moderate regional dyssynergy is common in primary DCM. On the other hand, global left ventricular dysfunction occurs in patients with diffuse coronary disease (10). In the study of Vigna et al (11) the baseline hypocontractility tended to be less homogenous in patients with ischemic DCM than in those with nonischemic DCM, however large overlaps in the individual data were observed.…”
TDE parameters: early diastolic velocity, preejection period, isovolumic relaxation time and the dispersion index of systolic velocities differentiate ischemic and nonischemic etiology of dilated cardiomyopathy.
“…Other noninvasive methods have been used to distinguish among ischemic and idiopathic cardiomyopathy, including echocardiography [15][16][17][18][19][20], radionuclide ventriculography [21,22], stress myocardial perfusion imaging [23][24][25][26], positron emission tomography [27,28] and electron beam computer tomography [29]. The success of these different approaches to distinguish between both etiologies of cardiomyopathy has been variable.…”
“…Two-dimensional echocardiography, in combination with Doppler and color flow imaging, although commonly used by clinicians, has limited accuracy to differentiate patients with nonischemic cardiomyopathy from those with ischemic cardiomyopathy. [27][28][29] Studies report that up to two-thirds of patients with nonischemic cardiomyopathy may have regional wall motion abnormalities at rest. 27 Myocardial perfusion imaging is also limited in reliably differentiating ischemic from nonischemic cardiomyopathy, since many patients with the latter have radionuclide evidence of LV segmental wall motion abnormalities, selective LV systolic dysfunction, and segmental perfusion abnormalities.…”
CTA appears as a clinically applicable accurate diagnostic modality to exclude ischemic etiology in patients with cardiomyopathy of undetermined cause and this further supports the appropriateness of the use of CTA to determine the cause of new onset cardiomyopathy of unknown etiology.
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