Usefulness of lipoprotein changes during acute coronary syndromes for predicting postdischarge lipoprotein levels

Henkin, Yaakov; Crystal, Eugene; Goldberg, Yury; Friger, Michael; Lorber, Jonathan; Zuili, I.; Shany, Shraga

doi:10.1016/s0002-9149(01)02154-3

Cited by 36 publications

(17 citation statements)

References 25 publications

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“…According to Pitt et al [31], mean lipid levels show little variation within 4 days of a coronary event; however, the investigation of Khawaja et al demonstrated that decreased levels of TG obtained within 24 h of admission were associated with higher long-term all-cause mortality in patients admitted with NSTEMI [32]. Moreover, Henkin et al found a significant decrease in the TG levels of ACS patients within the initial 24 h after admission, suggesting the lipid-lowering effect of heparin in the background [33]. Like the previous studies, most of our samples were taken within 24 h of the admission.…”

Section: Discussionmentioning

confidence: 99%

Changes in triglyceride, HDL-C, and non-HDL-C levels in patients with acute coronary syndrome

Koncsos

Fülöp

Juhász

et al. 2016

Wien Klin Wochenschr

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Section: Discussionmentioning

confidence: 99%

Changes in triglyceride, HDL-C, and non-HDL-C levels in patients with acute coronary syndrome

Koncsos

Fülöp

Juhász

et al. 2016

Wien Klin Wochenschr

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“…In order to mitigate this effect, blood samples were extracted within the first 24 hours after the cardiovascular episode if no blood test had been performed previously, since decreased HDL and triglyceride levels are of little relevance during this period. 25,26 Patient were diagnosed as metabolic syndrome if they have three of the following five NCEP: ATP III 2001 criteria; abdominal obesity (Waist circumference >102cm in male and >88cm in female), high triglyceride levels (>150mg/dl), low HDL-C levels (<40mg/dl in male and <50mg/dl in female), elevated fasting blood glucose (>110mg/dl) and high blood pressure (Systolic/diastolic blood pressure >130/85). Data were analyzed and interpreted using the student's t test and the chi-square test.…”

Section: Methodsmentioning

confidence: 99%

Prevalence of Metabolic Syndrome in Acute Myocardial Infarction Patients in a Tertiary Care Hospital in Chennai

Senthil¹,

Ramakrishnan²,

G³

et al. 2015

jemds

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OBJECTIVES:To ascertain the prevalence of metabolic syndrome (MS) and to assess the association between the metabolic syndrome and its individual components-fasting blood sugar (FBS), blood pressure (BP), HDL cholesterol (HDL-C), triglyceride (TGL) and waist circumference(WC) and the frequency of its definitive components in patients with acute myocardial infarction. (AMI) MATERIALS AND METHODS: This is a hospital based cross sectional study were 100 unselected patients with AMI categorized according to NCEP: ATP III 2001 CRITERIA were studied. STATISTICAL ANALYSIS: Data was analyzed using the student's t test and chi-square test. RESULTS: This study shows high prevalence of metabolic syndrome (53%) in patients with AMI. Hypertension (85%), Hyperglycemia (72%) and Dyslipidemia (70%) were found to be the most prevalent components of metabolic syndrome. CONCLUSION: This study shows that there is a strong correlation between metabolic syndrome and AMI with Hypertension followed by Hyperglycemia having the highest positive predictive value among its components.

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“…However, according to ATP III, a fasting lipoprotein profile obtained during the first 24 hours of hospital admission will produce a value quite close to an individual's actual baseline [41••]. Similarly, a study by Henkin et al [53] suggests that despite the changes in all lipoproteins that occur as early as 6 hours after hospital admission, LDL cholesterol levels during the initial 24 hours after admission can be used to determine which patients will require lipid-lowering medications. In this study, over 90% of patients with LDL cholesterol at or above 125 mg/dL and 100% with LDL cholesterol at or above 150 mg/dL on the morning after admission were candidates for statin therapy after discharge.…”

Section: Barriers To Implementation Of Treatmentmentioning

confidence: 99%

Lipid-lowering therapies in the management of acute coronary syndromes

Mosca

Biviano

2002

Curr Cardiol Rep

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Despite the significant advances made in the treatment of acute coronary syndromes (ACS) with antiplatelet and antithrombotic therapy, the risk of serious complications remains high, especially in the first few months following an acute coronary event. Although lipid-lowering therapy in patients with significant risk factors (primary prevention) or stable coronary disease (secondary prevention) is known to improve long-term survival, patients with a recent ACS were specifically excluded from the early statin trials. However, the use of lipid-lowering agents (principally statins) during hospitalization or in the period immediately following an acute coronary event has recently been studied. Statin therapy in this setting has been shown to reduce angina, rehospitalization, and mortality. Improved outcomes associated with lipid-lowering therapy in ACS may be mediated through beneficial effects on plaque stabilization, endothelial function, inflammation, and thrombus formation. This paper reviews the evidence supporting the potential benefits and mechanisms of statin therapy in the management of ACS. Clinical guidelines to achieve optimal lipid management are also discussed.

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Usefulness of lipoprotein changes during acute coronary syndromes for predicting postdischarge lipoprotein levels

Cited by 36 publications

References 25 publications

Changes in triglyceride, HDL-C, and non-HDL-C levels in patients with acute coronary syndrome

Changes in triglyceride, HDL-C, and non-HDL-C levels in patients with acute coronary syndrome

Prevalence of Metabolic Syndrome in Acute Myocardial Infarction Patients in a Tertiary Care Hospital in Chennai

Lipid-lowering therapies in the management of acute coronary syndromes

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