Usefulness of Magnetic Resonance in Patients With Invasive Cancer Eligible for Breast Conservation: A Comparative Study

Can algorithmically assessed MRI features predict which patients with a preoperative diagnosis of ductal carcinoma in situ are upstaged to invasive breast cancer?

“…Further, the value of this clinical information must be considered in light of the costs incurred by this additional testing, as well as which patients with DCIS would be most likely to benefit. This is especially a concern, as several studies have shown increased mastectomy rates associated with use of preoperative breast MRI . The future role for such radiogenomic approaches could lie in their ability to mitigate the interobserver variability inherent in single radiologist interpretation, and the potential for their use as a component of integrated diagnostic tools that can be refined to predict tumor biology.…”

Meta-analysis of the effect of preoperative breast MRI on the surgical management of ductal carcinoma in situ

“…Whether the use of preoperative MRI in women with DCIS translates into oncological advantages in terms of local control and survival is far from clear. In this regard, two recent studies reported no advantages for local control of DCIS in patients who underwent preoperative MRI and BCS.…”

“…In this regard, two recent studies reported no advantages for local control of DCIS in patients who underwent preoperative MRI and BCS. Furthermore, preoperative MRI has disadvantages, in that it increases the numbers of unnecessary surgical biopsies.…”

The role of preoperative breast magnetic resonance (MR) imaging for surgical decision in patients with triple‐negative breast cancer

“…However, preoperative breast MR imaging can detect about 11–24% of additional cancers and 2–4% of contralateral breast cancers . Paradoxically, preoperative breast MR imaging may trigger an additional 12% of mastectomies because of additionally detected breast lesions . In this study, the incidence of mastectomy performed due to a change in the surgical plan was 5.1% (47 cases), and the predominant reasons for the change in plan were multifocality and the detection of a tumor larger than that found on US examination.…”