Usefulness of right ventricular isovolumic relaxation time in predicting systolic pulmonary artery pressure

Elbaz, M.; Ramzy, Aly; Hassan, Amin

doi:10.1016/j.ehj.2013.12.078

Cited by 1 publication

(2 citation statements)

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“…This result is consistent with numerous Doppler catheterisation studies conducted from 1967 to 2016 [Table 3]. [3,[5][6][7][8][9]15,[18][19][20][21][22] All these studies compared RV IVRT measured by TDI with pulmonary artery systolic pressure measured invasively at catheterisation laboratory. We estimated pulmonary artery systolic pressure noninvasively by adding the estimated mean RAP (as per IVC diameter and respirophasic variation) and RV to RA pressure gradient from TR.…”

Section: Discussionsupporting

confidence: 85%

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Estimation of Elevated Systolic Pulmonary Artery Pressure Using Right Ventricular Isovolumic Relaxation Time

Arke

Babu

Borkar

2022

VJIM

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Objectives: Echocardiographic estimation of pulmonary hypertension (PH) in absence of tricuspid regurgitation (TR) remains a challenge. Isovolumic relaxation time (IVRT) measured by Doppler tissue imaging (DTI) can be a useful method to estimate PH. This study was designed to evaluate the feasibility and accuracy of the right ventricle (RV) IVRT for predicting PH. Material and Methods: We conducted an analytical cross-sectional study in 90 consecutive patients suspected or known to have pulmonary hypertension (PH). sPAP was assessed using TR jet velocity using a Bernoulli’s equation. RV IVRT was calculated using tissue Doppler imaging. Results: Out of the 90 consecutive patients [49 (54.4%) were female, mean age was 48 +/- 14 years and mean systolic pulmonary aretry pressure (sPAP) was 68.25+/- 29.15 mmHg. Mean RV IVRT was 67.29 ± 22.2 msec. We found a strong correlation between IVRT and systolic pulmonary pressure (r = 0.69, P < 0.0001) and a cutoff of 43 ms showed a sensitivity and specificity of 89% and 93%, respectively, for the prediction of elevated sPAP (≥39 mm Hg). However, this correlation reduces in the presence of RV dysfunction and elevated mean RA pressure. Conclusion: The calculation of IVRT by DTI is a simple and feasible method. It correlates well with sPAP. It is a useful echocardiographic parameter as a screening in patients at risk for PH, monitoring the disease progression and the effect of the treatment for PH, especially in patients with absent TR.

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Section: Discussionsupporting

confidence: 85%

“…Lindqvist et al, [9] 2006 n=26 --0.71 a (P<0.001) ----Bre'chot et al, [27] 2008 n=38 64±22 83±34 0.87 (P<0.0001) --10.8±1.3 -Cabrita et al, [8] 2013 n=196 81.4±24.7 110.5±29.2 0.5 (P<0.0001) 0.52 a (P<0.0001) 0.67±0.22 0.41 (P<0.001) 0.43 a (P<0.001) 10±2.5 -0.14 (P=0.04) -0.13 a (P=0.05) El-Baz et al, [21] 2014 n=30…”

Section: Discussionmentioning

confidence: 99%