Usefulness of the 15-item geriatric depression scale (GDS-15) for classifying minor and major depressive disorders among community-dwelling elders

Shin, Cheolmin; Park, Moon Ho; Lee, Seung-Hoon; Ko, Young Hoon; Kim, Yong Ku; Han, Kook Nam; Jeong, Hyun Ghang

doi:10.1016/j.jad.2019.08.053

Cited by 106 publications

(76 citation statements)

References 44 publications

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“…However, research validating their effectiveness in minority groups in the United States such as non-Hispanic Black and Hispanic populations is largely lacking. Although cognitive function can affect the GDS-15 score, it is still an appropriate tool for older adults with different levels of cognitive function ( Conradsson et al, 2013 ; Shin et al, 2019 ). It is important to note that the GDS-15 has a higher validity among older adults with less cognitive impairment ( Conradsson et al, 2013 ).…”

Section: Resultsmentioning

confidence: 99%

Evidence for the 4Ms: Interactions and Outcomes across the Care Continuum

et al. 2021

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Objectives: An expert panel reviewed and summarized the literature related to the evidence for the 4Ms—what matters, medication, mentation, and mobility—in supporting care for older adults. Methods: In 2017, geriatric experts and health system executives collaborated with the Institute for Healthcare Improvement (IHI) to develop the 4Ms framework. Through a strategic search of the IHI database and recent literature, evidence was compiled in support of the framework’s positive clinical outcomes. Results: Asking what matters from the outset of care planning improved both psychological and physiological health statuses. Using screening protocols such as the Beers’ criteria inhibited overprescribing. Mentation strategies aided in prevention and treatment. Fall risk and physical function assessment with early goals and safe environments allowed for safe mobility. Discussion: Through a framework that reduces cognitive load of providers and improves the reliability of evidence-based care for older adults, all clinicians and healthcare workers can engage in age-friendly care.

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Section: Resultsmentioning

confidence: 99%

Evidence for the 4Ms: Interactions and Outcomes across the Care Continuum

et al. 2021

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“…In the two groups sorted by GDS, the participants' clinical characteristics and psychological measures are listed in Table 1. Based on previous studies, GDS was divided into a normal group and a depressed group (cut‐off point: 4/5) 34–38 . There was no significant difference between these groups in terms of MMSE score ≥ 24 points ( P = 0.12), which is an index of cognitive function, but there was a significant difference in CDR score of ≤0.5 between the groups ( P = 0.02).…”

Section: Resultsmentioning

confidence: 99%

No association of both serum pro‐brain‐derived neurotrophic factor (proBDNF) and BDNF concentrations with depressive state in community‐dwelling elderly people

et al. 2021

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Background Brain‐derived neurotrophic factor (BDNF) is involved in emotional and cognitive function. Low‐BDNF levels occur in patients with depression, while proBDNF, a precursor of BDNF with the opposite physiological function, increases in major depression. However, it is unclear whether BDNF and proBDNF are associated with depression in the elderly. The present study aimed to investigate whether serum proBDNF and BDNF are associated with depressive state in community‐dwelling elderly people. Methods This was a cross‐sectional study conducted in Kurogawa‐cho Imari, Saga Prefecture, Japan, in people aged ≥65 years. Depressive state was assessed using the Geriatric Depression Scale‐Short Form (Japanese version) (GDS). Of the 274 patients who undertook the GDS, those with a medical history affecting cognitive function were excluded, as were those with Mini‐Mental State Examination score ≥ 24 or a Clinical Dementia Rating < 0.5. Further, we used delayed recall of ‘logical memory A’ from the Wechsler Memory Scale‐Revised (LMII‐DR) for memory assessment. Results The final sample consisted of 155 individuals (mean age 75.4 ± 6.8 years; 55 men, mean age 74.8 ± 5.9 years; 100 women, mean age 76.3 ± 7.1 years). In the GDS, 139 participants showed a normal score (0–4) and 16 showed depressive tendencies or depression (score: ≥ 5). After examining confounders of the GDS, logistic regression using categorical covariates showed a negative significant difference between depressive state and serum BDNF in the low‐BDNF group only, with a positive correlation in the trend test. None of the analyses showed any association between GDS and proBDNF levels. Conclusion ProBDNF and BDNF levels seemed not to be associated with depressive state in community‐dwelling elderly people.

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“…We selected all the cohort patients over 60 years of age for this study. Although the cut-off between geriatric PLOS ONE and non-geriatric depression remains unclear, ranging from 60 [1,7,25,26] to 65 years old [27,28], we chose the age of 60 in order to compare our findings with those of the majority of studies focusing on the impact of CM in depressive disorders [1,7,25,26]. Before participating in the full assessment, the patients were interviewed by a psychiatrist at the expert centre in order to:…”

Section: Methodsmentioning

confidence: 99%

Relationship between childhood physical abuse and clinical severity of treatment-resistant depression in a geriatric population

Yrondi

Arbus²,

Bennabi³

et al. 2021

PLoS ONE

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Introduction We assessed the correlation between childhood maltreatment (CM) and severity of depression in an elderly unipolar Treatment-Resistant Depression (TRD) sample. Methods Patients were enrolled from a longitudinal cohort (FACE-DR) of the French Network of Expert TRD Centres. Results Our sample included 96 patients (33% of the overall cohort) aged 60 years or above, with a mean age of 67.2 (SD = 5.7). The majority of the patients were female (62.5%). The Montgomery and Asberg Depression Rating Scale (MADRS) and Quick Inventory Depression Scale-Self Report (QIDS-SR) mean scores were high, 28.2 (SD = 7.49) [MADRS score range: 0–60; moderate severity≥20, high severity≥35] and 16.5 (SD = 4.94) [IDS-SR score range: 0–27; moderate severity≥11, high severity≥16], respectively. Mean self-esteem scores were 22.47 (SD = 6.26) [range 0–30]. In an age- and sex-adjusted model, we found a positive correlation between childhood trauma (CTQ scores) and depressive symptom severity [MADRS (β = 0.274; p = 0.07) and QIDS-SR (β = 0.302; p = 0.005) scores]. We detected a statistically significant correlation between physical abuse and depressive symptom severity [MADRS (β = 0.304; p = 0.03) and QIDS-SR (β = 0.362; p = 0.005) scores]. We did not observe any significant correlation between other types of trauma and depressive symptom severity. We showed that self-esteem (Rosenberg scale) mediated the effect of physical abuse (PA) on the intensity of depressive symptoms [MADRS: b = 0.318, 95% BCa C.I. [0.07, 0.62]; QIDS-SR: b = 0.177, 95% BCa C.I. [0.04, 0.37]]. Preacher & Kelly’s Kappa Squared values of 19.1% (k2 = 0.191) and 16% (k2 = 0.16), respectively for the two scales, indicate a moderate effect. Conclusion To our knowledge, this is the first study conducted in a geriatric TRD population documenting an association between childhood trauma (mainly relating to PA) and the intensity of depressive symptoms.

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Usefulness of the 15-item geriatric depression scale (GDS-15) for classifying minor and major depressive disorders among community-dwelling elders

Cited by 106 publications

References 44 publications

Evidence for the 4Ms: Interactions and Outcomes across the Care Continuum

Evidence for the 4Ms: Interactions and Outcomes across the Care Continuum

No association of both serum pro‐brain‐derived neurotrophic factor (proBDNF) and BDNF concentrations with depressive state in community‐dwelling elderly people

Relationship between childhood physical abuse and clinical severity of treatment-resistant depression in a geriatric population

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