Usefulness of the Monocyte-To-High-Density Lipoprotein Cholesterol Ratio to Predict Bare Metal Stent Restenosis

Yılmaz, Samet; Akboğa, Mehmet Kadri; Şen, Fatih; Balcı, Kevser Gülcihan; Aras, Dursun; Temizhan, Ahmet; Aydoğdu, Sinan

doi:10.2217/bmm-2016-0069

Cited by 40 publications

(28 citation statements)

References 37 publications

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“…2,3 Inflammation and oxidative stress are involved in atherosclerosis and are thought to contribute to the initiation and progression of ISR. 3,4 Many inflammatory and oxidative biomarkers including C-reactive protein (CRP), monocyte-to-HDL-C cholesterol ratio (MHR), and resting heart rate have been demonstrated to be independent risk factors for atherosclerosis, ISR, and cardiovascular events. [3][4][5][6] In the study by Kundi et al, it was clear that the white blood cell count was higher, whereas neutrophil and lymphocyte count were lower in the ISR (þ) group when compared to the ISR (À) group ( Table 2).…”

mentioning

confidence: 99%

Predictors of In-Stent Restenosis in Patients With Stable Angina Pectoris

Yılmaz¹,

Akboğa²,

Topaloğlu³

2017

Angiology

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confidence: 99%

Predictors of In-Stent Restenosis in Patients With Stable Angina Pectoris

Yılmaz¹,

Akboğa²,

Topaloğlu³

2017

Angiology

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“…Likewise, MHR was found to be independently correlated with inhospital major adverse cardiac events and mortality after primary percutaneous coronary intervention (PCI) [45], and with major adverse cardiovascular events in patients undergoing coronary angiography [46] and in patients with acute coronary syndrome (ACS) [47]. Moreover, MHR arose as an independent predictor of in-stent restenosis [48]. As stated above, several lines of reports, which referred the benefit of monocyte countapplied predictive markers for CVD, were augmented.…”

Section: Modified Marker Using Monocyte Count Correlates With Cardiovmentioning

confidence: 99%

Potential of Monocyte Count for the Assessment of Cardiovascular Disease

Matsumura¹,

Yamamoto²,

Tsujita³

et al. 2017

Cardiovasc Pharm Open Access

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Atherosclerosis is a chronic inflammatory disease proceeding from an imbalance in lipid metabolism and immune responses. Since leukocytes, especially monocytes and monocyte-derived macrophages, play pivotal roles in the progression of atherosclerosis, it is possible that monocyte count is a beneficial marker for predicting cardiovascular disease (CVD). Many epidemiologic and clinical studies have indicated monocytosis to be an independent predictor of cardiovascular events, both in healthy individuals at baseline and in patients with CVD or with high risk diseases for CVD, such as diabetes, dyslipidemia, hypertension and chronic kidney disease. This relationship has been observed in prospective and retrospective cohort studies, and endures after adjustment for several CVD risk factors. Other indicators utilized monocyte count, such as lymphocyte-to-monocyte ratio, monocyte-to-lymphocyte ratio and monocyte-to-high-density lipoprotein cholesterol ratio, were also independently associated with cardiovascular events and its mortality. In this review, we discussed the clinical utility of the monocyte count as a predictive marker in atherosclerotic diseases.

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“…It was reported that neointimal hyperplasia was triggered by stents, and ISR could result from several mechanisms including inflammation and oxidative stress. [2][3][4] In our recent study, we demonstrated that CHA 2 DS 2 -VASc (congestive heart failure, hypertension, age 75 years, diabetes mellitus, previous stroke/transient ischemic attack, vascular disease, age 65-74 years, female gender) score could be also used as a predictor of ISR. 5 We also found a significant positive correlation between CHA 2 DS 2 -VASc score and C-reactive protein levels.…”

Section: Et Al Reported In Their Recent Article Entitled "Evaluatimentioning

confidence: 99%