Usefulness of the Vall d’Hebron Risk Score to stratify the risk of patients with ischemic cardiomyopathy

Romero-Farina, Guillermo; Aguadé-Bruix, Santiago; Ródenas-Alesina, Eduard; Herrador, Lorena; Jordán, Pablo; Ferreira‐González, Ignacio

doi:10.1007/s12350-022-03074-6

Cited by 2 publications

(2 citation statements)

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“…Recently in a new series of 673 patients with previous MI and/or CR with LVEF ≤40% (ischaemic cardiomyopathy) who underwent gated SPECT, VH-RS for risk stratification was used. 21 These patients were stratified into five-risk levels: VLR, LR, MR, HR and very HR (> 6%/year) for MACEs (MI, CD, CR and heart failure hospitalisation). In addition, the cardiac resynchronisation therapy and the implantable cardioverter defibrillator were investigated.…”

Section: Validation Groupmentioning

confidence: 99%

“…VH-RS was effective in evaluating risk of patients with stable ischaemic cardiomyopathy (AUC: 0.82, p<0.001). 21 In VH-RS-II, the risk of each patient was analysed and then grouped into four risk levels: VLR (≤0.4%/year); LR (0.5 to <1%/year); MR (≥1 to <3%/year) and HR (≥3%/year) with a mean 4-year follow-up. The majority of patients without previous MI and/or CR had VLR (63.8%).…”

Section: Validation Groupmentioning

confidence: 99%

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Vall d’Hebron Risk Score II for myocardial infarction and cardiac death

Romero-Farina,

Aguadé-Bruix,

Ferreira González

2023

Open Heart

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ObjectivesThe aim of this study was to create a new Vall d’Hebron Risk Score-II (VH-RS-II) for non-fatal myocardial infarction (MI) and/or cardiac death (CD), excluding patients with coronary revascularisation (CR) during the follow-up.MethodsWe analysed 5215 consecutive patients underwent gated single photon emission CT (SPECT); 2960 patients (age 64.2±11, male 58.1%) had no previous MI and/or CR, and 2255 patients (age 63.3±11, male 81.9%) had previous MI and/or CR. During a follow-up of 4.3±2.6 years, the cardiac event (MI and CD) was evaluated. This study was reviewed and approved by the ethics committee of our institution (number form trial register, PR(AG)168.2012). To obtain the predictor model, multivariate Cox regression analysis and multivariate logistic regression analysis were used. RS-VH-II was validated with 679 patients.ResultsIn patients without previous MI and/or CR, age (HR: 1.01; p<0.001), diabetes (HR: 2.1, p=0.001), metabolic equivalent (METs) (HR: 0.89, p=0.038), ST segment depression (HR: 1.4, p=0.011), ejection fraction (EF) (HR: 0.97, p<0.001) and summed stress score (HR: 1.2, p<0.001) were the independent predictors of CE (C-statistic: 0.8). In patients with previous MI and/or CR, age (HR: 1.06, p<0.001), male (HR: 1.9, p=0.047), smoker (HR: 1.5, p=0.047), METs (HR: 0.8, p<0.001), ST segment depression (HR: 1.4, p=0.002), EF (HR: 0.96; p<0.001) and summed difference score (HR: 1.03, p=0.06) were the independent predictors of CE (C-statistic:0.8).ConclusionThe VH-RS-II obtained from different clinical exercise and gated SPECT variables allow the risk stratification for MI and CD in patients with or without previous MI and/or CR in due form.

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Section: Validation Groupmentioning

confidence: 99%

Section: Validation Groupmentioning

confidence: 99%