Usefulness of urinary fibronectin and laminin as biomarkers of glomerular injury in diabetics in Port Harcourt, Nigeria

Orih, Michael Chinwe; Obiorah, Christopher Chinedu

doi:10.5897/jde2020.0137

J. Diabetes Endocrinol.

2020

DOI: 10.5897/jde2020.0137

|View full text |Cite

Usefulness of urinary fibronectin and laminin as biomarkers of glomerular injury in diabetics in Port Harcourt, Nigeria

Michael Chinwe Orih¹,

Christopher Chinedu Obiorah²

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2021

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

The burden of diabetic kidney disease in Nigeria − systematic review and meta-analysis

Azeez

Efuntoye²,

Abiola³

et al. 2021

Journal of the Egyptian Society of Nephrology and Transplantation

View full text Add to dashboard Cite

Background Diabetic kidney disease (DKD) is a microvascular complication of diabetes mellitus. Considering that the burden of diabetes mellitus is rising in Nigeria, there is a need to ascertain the burden of one of its most common complications. The objective of the meta-analysis was to determine the pooled prevalence of DKD in Nigeria and identify its risk factors. Patients and methods The study is a meta-analysis and it followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Google scholar, PubMed, AJOL, SCOPUS, medRxiv, and the gray literature were systematically searched using appropriate key terms. Statistical analysis was done with MetaXL. The inverse-variance heterogeneity model was used for the meta-analysis and heterogeneity was determined using the I 2 statistic and the Cochran's Q test. Publication bias was checked with the Doi plot and LFK index. Results Nineteen studies met the eligibility criteria. The total sample size was 56 571. The pooled prevalence of DKD in Nigeria was 28% (95% confidence interval 3–58). The Cochran's Q was 747 (P<0.001), while the I 2 statistic was 97.6%. The Doi plot was drawn and the LFK index was 6.22. The most common risk factors for DKD were suboptimal glycemic control, hypertension, obesity, duration of diabetes, male sex, and advancing age. Conclusion The prevalence of DKD in Nigeria is high and greater attention should be focused on managing the risk factors so as to alleviate the burden of the disease.

show abstract

The burden of diabetic kidney disease in Nigeria − systematic review and meta-analysis

Azeez

Efuntoye²,

Abiola³

et al. 2021

Journal of the Egyptian Society of Nephrology and Transplantation

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Usefulness of urinary fibronectin and laminin as biomarkers of glomerular injury in diabetics in Port Harcourt, Nigeria

Cited by 1 publication

References 14 publications

The burden of diabetic kidney disease in Nigeria − systematic review and meta-analysis

The burden of diabetic kidney disease in Nigeria − systematic review and meta-analysis

Contact Info

Product

Resources

About