1992
DOI: 10.1001/archpedi.1992.02160220046019
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Uses and Technique of Pediatric Lumbar Puncture

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Cited by 8 publications
(9 citation statements)
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“…Proposals have been made to perform laboratory testing on CSF in a logical sequence, relying on standard tests such as cell count, differential, protein and glucose concentrations, and Gram staining to guide the decision to order additional testing (10,19,25,27,29). The cell count and differential in CSF have been shown to be sensitive indicators of bacterial meningitis, more so than glucose and protein concentration estimations, which are often nonspecific and of limited diagnostic value (13,19,29,(34)(35)(36). Using a WBC count of Ն50 cells per mm 3 as a criterion for performing BAT, Werner and Kruger (36) achieved 100% sensitivity in predicting BA-positive specimens (36).…”
Section: Discussionmentioning
confidence: 99%
“…Proposals have been made to perform laboratory testing on CSF in a logical sequence, relying on standard tests such as cell count, differential, protein and glucose concentrations, and Gram staining to guide the decision to order additional testing (10,19,25,27,29). The cell count and differential in CSF have been shown to be sensitive indicators of bacterial meningitis, more so than glucose and protein concentration estimations, which are often nonspecific and of limited diagnostic value (13,19,29,(34)(35)(36). Using a WBC count of Ն50 cells per mm 3 as a criterion for performing BAT, Werner and Kruger (36) achieved 100% sensitivity in predicting BA-positive specimens (36).…”
Section: Discussionmentioning
confidence: 99%
“…In patients who have been partially treated with antibiotics or who are immunosuppressed, the clinical features of meningitis may be more subtle and there should be a lower threshold for performing LP in this group 8 . Lumbar puncture is often used as a test of exclusion in the presence of febrile seizures in children, and fever and delirium in the elderly; although the diagnostic yield in these situations is low in the absence of other supportive clinical parameters 9–15 …”
Section: Indicationsmentioning
confidence: 99%
“…However, antibiotic therapy should not be withheld once the diagnosis is clinically suspected as the organism may still be identified in the CSF or by blood culture and CSF antigen testing 24–26 . The classical findings of high protein, low glucose and neutrophil pleocytosis will often persist for several days 13,24,25,60–62 …”
Section: Csf Interpretationmentioning
confidence: 99%
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“…Although LP in children was initially described in 1878, 1 we are unaware of any studies which explain physicians' training, preferred techniques, and use of analgesics in this patient population. Although LP in children was initially described in 1878, 1 we are unaware of any studies which explain physicians' training, preferred techniques, and use of analgesics in this patient population.…”
mentioning
confidence: 99%