2021
DOI: 10.1073/pnas.2019893118
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Using artificial intelligence to improve COVID-19 rapid diagnostic test result interpretation

Abstract: Serological rapid diagnostic tests (RDTs) are widely used across pathologies, often providing users a simple, binary result (positive or negative) in as little as 5 to 20 min. Since the beginning of the COVID-19 pandemic, new RDTs for identifying SARS-CoV-2 have rapidly proliferated. However, these seemingly easy-to-read tests can be highly subjective, and interpretations of the visible “bands” of color that appear (or not) in a test window may vary between users, test models, and brands. We developed and eval… Show more

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Cited by 46 publications
(44 citation statements)
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“…Machine learning-based approaches had been widely utilized in understanding the epidemiology, clinical presentation, and outcomes of COVID-19, as well as its vaccine acceptance sentiments and vaccine side effects [49][50][51][52][53][54]. Artificial intelligence (AI) models could be as accurate as medical specialists in the diagnosis and prognosis of COVID-19; however, their current diagnostic accuracy needs to be improved through further integration of big datasets of radiographic and clinical information [49].…”
Section: Introductionmentioning
confidence: 99%
“…Machine learning-based approaches had been widely utilized in understanding the epidemiology, clinical presentation, and outcomes of COVID-19, as well as its vaccine acceptance sentiments and vaccine side effects [49][50][51][52][53][54]. Artificial intelligence (AI) models could be as accurate as medical specialists in the diagnosis and prognosis of COVID-19; however, their current diagnostic accuracy needs to be improved through further integration of big datasets of radiographic and clinical information [49].…”
Section: Introductionmentioning
confidence: 99%
“…For this issue, AI could be an excellent solution. Recently, Mendels et al applied AI to improve test result interpretations of conventional LFIA assay for COVID-19 detection [ 133 ]. By developing their smartphone app, xRCovid, they largely removed human errors using machine learning.…”
Section: Role Of Smartphones In Disease Control and Surveillance During The Covid-19 Pandemicmentioning
confidence: 99%
“…Test results can be provided in 5–8 min with a high sensitivity of 97.4% and a specificity of 98.3%. Figure 10 shows a schematic diagram of a portable AI-aided smartphone LFIA system for COVID-19 detection based upon the above-mentioned research work [ 61 , 133 , 134 ].…”
Section: Role Of Smartphones In Disease Control and Surveillance During The Covid-19 Pandemicmentioning
confidence: 99%
See 1 more Smart Citation
“…10 AI based smartphone applications using machine learning can classify SARS-CoV-2 serological rapid diagnostic test results, reducing reading errors in comparison to reading by the naked eye thereby improving result interpretation. 11 AI in the field of cardiology during the pandemic has proven to be useful in providing advanced technologybased treatment and to predict the survival/mortality of a COVID-19 patient from heart failure. 12 By using algorithms, AI can predict and help treat complex heartrelated problems of COVID-19 patients, monitor information, raise timely alerts, repeatedly learn from the input dataset, assess congenital heart disease, angina and fibrillation issues.…”
Section: Aimentioning
confidence: 99%