Using chitosan, hyaluronic acid, alginate, and gelatin-based smart biological hydrogels for drug delivery in oral mucosal lesions: A review

Stimuli-responsive peptide hydrogels for biomedical applications

“…16 Frequently employed stimuli-responsive hydrogels encompass synthetic polymers such as polyethylene glycol (PEG), 17 polyvinyl alcohol (PVA), 18,19 or poly(2-hydroxyethyl methacrylate) (PHEMA), 20,21 alongside naturally derived compounds such as agarose, alginate, chitosan, and gelatin. [22][23][24][25] Although these conventional hydrogels are readily accessible, their limitations in terms of biocompatibility, biodegradability, tunability, and other features curtail their scope within the biomedical arena. Peptides, a category of short chains composed of amino acids, epitomize an optimal selection of materials for the construction of stimuli-responsive hydrogels due to their excellent, controllable self-assembly, and notable biological activity.…”

Stimuli-responsive hydrogel based on natural polymers for breast cancer

“…Moreover, natural hydrogels encompass different functional moieties such as -NH2, -COOH, -OH, and others, making them responsive to various stimuli. Since systemic DDSs remain harmless to the rest of the body, smart hydrogels hold great promise as smart materials for the local implementation of precision therapies for breast cancer ( Samiraninezhad et al, 2023 ).…”

Novel alginate nanoparticles for the simultaneous delivery of iron and folate: a potential nano-drug delivery system for anaemic patients

“…16 Alginate hydrogels have diverse applications, including drug delivery, tissue engineering, and wound healing. 17 For instance, Katuwavila et al successfully synthesized ferrous-encapsulated alginate nanoparticles with 75% encapsulation efficiency. 18 Additionally, folic acid encapsulation in alginate–pectin nanoparticles demonstrated promising pH-sensitive controlled release with 70% encapsulation efficiency.…”