Using cranial electrotherapy stimulation to treat pain associated with spinal cord injury

Tan, Gabriel; Rintala, Diana H.; Thornby, John; Yang, June; Wade, Walter H.; Vasilev, Christine

doi:10.1682/jrrd.2005.04.0066

Cited by 45 publications

(34 citation statements)

References 46 publications

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“…In a pilot study, Tan et al 85 examined the effects of daily 1-hour treatment for 21 days on pain intensity and interference with activities in 38 male patients with SCI who were randomized to receive active CES (n = 18) or sham CES (n = 20). The active CES group reported significantly decreased daily pain intensity and pain interference compared with the sham CES group.…”

Section: Cranial Electrotherapy Stimulationmentioning

confidence: 99%

Invasive and non-invasive brain stimulation for treatment of neuropathic pain in patients with spinal cord injury: A review

Nardone

Höller

Leis

et al. 2013

The Journal of Spinal Cord Medicine

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Context: Past evidence has shown that invasive and non-invasive brain stimulation may be effective for relieving central pain.Objective: To perform a topical review of the literature on brain neurostimulation techniques in patients with chronic neuropathic pain due to traumatic spinal cord injury (SCI) and to assess the current evidence for their therapeutic efficacy. Methods: A MEDLINE search was performed using following terms: "Spinal cord injury", "Neuropathic pain", "Brain stimulation", "Deep brain stimulation" (DBS), "Motor cortex stimulation" (MCS), "Transcranial magnetic stimulation" (TMS), "Transcranial direct current stimulation" (tDCS), "Cranial electrotherapy stimulation" (CES). Results: Invasive neurostimulation therapies, in particular DBS and epidural MCS, have shown promise as treatments for neuropathic and phantom limb pain. However, the long-term efficacy of DBS is low, while MCS has a relatively higher potential with lesser complications that DBS. Among the non-invasive techniques, there is accumulating evidence that repetitive TMS can produce analgesic effects in healthy subjects undergoing laboratory-induced pain and in chronic pain conditions of various etiologies, at least partially and transiently. Another very safe technique of non-invasive brain stimulation -tDCS -applied over the sensorymotor cortex has been reported to decrease pain sensation and increase pain threshold in healthy subjects. CES has also proved to be effective in managing some types of pain, including neuropathic pain in subjects with SCI. Conclusion: A number of studies have begun to use non-invasive neuromodulatory techniques therapeutically to relieve neuropathic pain and phantom phenomena in patients with SCI. However, further studies are warranted to corroborate the early findings and confirm different targets and stimulation paradigms. The utility of these protocols in combination with pharmacological approaches should also be explored.

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Section: Cranial Electrotherapy Stimulationmentioning

confidence: 99%

Invasive and non-invasive brain stimulation for treatment of neuropathic pain in patients with spinal cord injury: A review

Nardone

Höller

Leis

et al. 2013

The Journal of Spinal Cord Medicine

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“…There have been reports of slight irritation at the electrode sites [39], burns at the electrode site [47], slight dizziness [43], headache [48], giddiness [48], and tooth pain [48]. In a recent study, Tan et al found CES to be effective in relieving musculoskeletal and neuropathic pain in persons with spinal cord injury (SCI) [49]. Not only was there a significant difference in the decrease in pain from before to after daily sessions between those who received active CES versus those who received sham CES, but also there was a significant change in pain interference with several quality-of-life domains from pre- to postintervention.…”

Section: Introductionmentioning

confidence: 99%

Feasibility of Using Cranial Electrotherapy Stimulation for Pain in Persons with Parkinson's Disease

Rintala

Tan

Willson

et al. 2010

Parkinson's Disease

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Objectives. To assess the feasibility of treating musculoskeletal pain in the lower back and/or lower extremities in persons with Parkinson's disease (PD) with cranial electrotherapy stimulation (CES). Design. Randomized, controlled, double-blind trial. Setting. Veterans Affairs Medical Center, Community. Participants. Nineteen persons with PD and pain in the lower back and/or lower extremities. Thirteen provided daily pain rating data. Intervention. Of the thirteen participants who provided daily pain data, 6 were randomly provided with active CES devices and 7 with sham devices to use at home 40 minutes per day for six weeks. They recorded their pain ratings on a 0-to-10 scale immediately before and after each session. Main Outcome Measure. Average daily change in pain intensity. Results. Persons receiving active CES had, on average, a 1.14-point decrease in pain compared with a 0.23-point decrease for those receiving sham CES (Wilcoxon Z = −2.20, P = .028). Conclusion. Use of CES at home by persons with PD is feasible and may be somewhat helpful in decreasing pain. A larger study is needed to determine the characteristics of persons who may experience meaningful pain reduction with CES. Guidelines for future studies are provided.

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“…This burden can create an added risk for psychological morbidity 8,11,12 and reduced well-being, [13][14][15][16] and also place significant limitations on physical and social functioning. 4,17 Research shows that pharmacological, 16,18 nonpharmacological, [19][20][21] and psychological [22][23][24] treatments of chronic pain can provide some relief for some individuals with physical disabilities. However, all of the available treatments have limitations, which include (1) a lack of meaningful efficacy for the majority of individuals, (2) absence of evidence for long-term beneficial effects, (3) high costs, and (4) for some treatments, significant side effects.…”

mentioning

confidence: 99%

Effects of a Tailored Positive Psychology Intervention on Well-Being and Pain in Individuals With Chronic Pain and a Physical Disability

Müller

Gertz

Molton

et al. 2016

The Clinical Journal of Pain

138

129

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Using cranial electrotherapy stimulation to treat pain associated with spinal cord injury

Cited by 45 publications

References 46 publications

Invasive and non-invasive brain stimulation for treatment of neuropathic pain in patients with spinal cord injury: A review

Invasive and non-invasive brain stimulation for treatment of neuropathic pain in patients with spinal cord injury: A review

Feasibility of Using Cranial Electrotherapy Stimulation for Pain in Persons with Parkinson's Disease

Effects of a Tailored Positive Psychology Intervention on Well-Being and Pain in Individuals With Chronic Pain and a Physical Disability

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