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BackgroundThe mass media have been used as a way of delivering preventive health messages. They have the potential to reach and to modify the knowledge, attitudes and behaviour of a large proportion of the community.ObjectivesTo evaluate the effectiveness of mass media interventions to prevent smoking in young people in terms of reduced smoking uptake, in addition to secondary outcomes including improved smoking outcomes, attitudes, behaviours, knowledge, self‐efficacy and perception.Search methodsWe searched the Cochrane Tobacco Addiction Group Specialised Register and conducted additional searches of MEDLINE and EMBASE in July 2010.Selection criteriaRandomized trials, controlled trials without randomization and time series studies that assessed the effectiveness of mass media campaigns (defined as channels of communication such as television, radio, newspapers, bill boards, posters, leaflets or booklets intended to reach large numbers of people and which are not dependent on person to person contact) in influencing the smoking behaviour (either objective or self‐reported) of young people under the age of 25 years.Data collection and analysisInformation relating to the characteristics and the content of media interventions, participants, outcomes, methods of the study and risk of bias was abstracted by two independent reviewers. Studies were combined using qualitative narrative synthesis.Main resultsSeven out of a total of 84 studies reporting information about mass media smoking campaigns met all of the inclusion criteria. All seven studies used a controlled trial design. Three studies concluded that mass media reduced the smoking behaviour of young people. All of the effective campaigns had a solid theoretical basis, used formative research in designing the campaign messages, and message broadcast was of reasonable intensity over extensive periods of time.Authors' conclusionsThere is some evidence that mass media can prevent the uptake of smoking in young people, however the evidence is not strong and contains a number of methodological flaws.Plain Language SummaryCan mass media campaigns (television, radio, newspapers, billboards and booklets) deter young people from starting to smokeCampaigns which researched and developed their message to reach their target audience had a higher success rate than those which did not. Overall, effective campaigns lasted longer with a minimum of three consecutive years, and were also more intense than less successful ones for both school based lessons (minimum eight lessons per grade) and media spots (minimum 4 weeks' duration across multiple media channels with between 167 and 350 TV and radio spots). The timing and type of broadcast made a difference to their success, with older youths in one study preferring radio to television. Implementation of combined school based curriculum/components (i.e. school posters) and the use of repetitive media messages delivered via multiple channels (i.e. newspapers, radio, television) over a minimum period of three years contributed to successful campaigns. Changes in attitudes, knowledge or intention to smoke did not generally seem to affect the long‐term success of the campaigns.
BackgroundNonsteroidal anti‐inflammatory drugs (NSAIDs) are used for pain relief following tonsillectomy in children. However, as they inhibit platelet aggregation and prolong bleeding time, they could cause increased perioperative bleeding. The overall risk remains unclear. This review was originally published in 2004 and was updated in 2010.ObjectivesThe primary objective of this review was to assess the effects of NSAIDs on bleeding with paediatric tonsillectomy. Our secondary outcome was to establish whether NSAIDs affect the incidence of other postoperative complications when compared to other forms of analgesia.Search methodsWe searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2010, Issue 6); MEDLINE (inception until May 2010); EMBASE (inception until May 2010); Current Problems (produced by the UK Medicines Control Agency), MedWatch (produced by the US Food and Drug Administration) and the Australian Adverse Drug Reactions Bulletins (to May 2010). The original search was performed in August 2004. We also contacted manufacturers and researchers in the field.Selection criteriaWe included randomized controlled trials assessing NSAIDs in children, up to and including 16 years of age, undergoing elective tonsillectomy or adenotonsillectomy.Data collection and analysisTwo authors independently assessed trial quality and extracted the data. We contacted study authors for additional information, where necessary.Main resultsWe included 15 trials that involved 1046 children in this updated review. This included one trial that was added as a result of updating our search and another trial that we had incorrectly excluded from our previous review. All included trials compared NSAIDs with other analgesics or placebo and looked at bleeding requiring surgical intervention. NSAIDs did not significantly alter the number of perioperative bleeding events requiring surgical intervention: Peto odds ratio (OR) 1.32 (95% confidence interval (CI) 0.47 to 3.70). Eight trials involving 532 children looked at bleeding not requiring surgical intervention. NSAIDs did not significantly alter the number of perioperative bleeding events not requiring surgical intervention: Peto OR 1.00 (95% CI 0.39 to 2.53). Twelve trials involving 928 children looked at postoperative nausea and vomiting. There was less nausea and vomiting when NSAIDs were used as part of the analgesic regime than when NSAIDs were not used: OR 0.49 (95% CI 0.29 to 0.83).Authors' conclusionsNSAIDs did not cause any increase in bleeding that required a return to theatre. There was significantly less nausea and vomiting when NSAIDs were used compared to alternative analgesics.Plain Language SummaryNonsteroidal anti‐inflammatory drugs (NSAIDs) do not significantly increase bleeding in children having their tonsils out, and there is less nausea and vomiting when NSAIDs are used.Nonsteroidal anti‐inflammatory drugs (NSAIDs) are used for pain relief following tonsillectomy in children. Bleeding is a recognised complication of this procedure but NSAIDs can interfere with blood clotting so there has been concern that these drugs will increase the risk of bleeding. If bleeding is severe this may result in the child being re‐admitted to hospital, having a blood transfusion or returning to theatre. It was therefore important to establish whether these drugs are safe to use in children having their tonsils out. The review focused on clinically significant bleeding that results in the child requiring additional treatment rather than measured blood loss.We also wanted to establish whether NSAIDs affect the incidence of other postoperative complications when compared to other forms of analgesia.The review found that NSAIDs did not significantly increase bleeding. There were insufficient data to compare the risk of bleeding with each individual type of NSAID. However, we were able to compare ketorolac, which has been perceived as having a greater risk of bleeding, with the other NSAIDs and found no increased risk of bleeding. There was less nausea and vomiting when NSAIDs were used as part of the analgesic regime than when NSAIDs were not used.The main limitation of our review is that bleeding following tonsillectomy is an uncommon event (occurring in 3% to 5% of children). We found all the data that are currently available (15 trials studying approximately 1000 children) but a very large number of participants are required to provide an adequate number of events to give a significant result. It is possible that the numbers of participants are too small to establish whether NSAIDs increase bleeding. However, currently there is no evidence to support withholding NSAIDs for paediatric tonsillectomy.
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