With the effective use of technological tools and equipment in all areas of life, the effective use of technological applications that will support the solution of daily life problems has become inevitable in order for science literacy to occur. The main purpose of this research is to determine the effect of infographic applications on the development of students' technological competencies and science literacy in the hybrid education process in high school physics courses. The study was carried out with 173 students in Turkey in the fall semester of the 2020-2021 academic years, for three weeks at school where the researcher taught. Quantitative and qualitative methods were used together within the scope of action research. Quantitative findings were evaluated with t-test and qualitative findings were evaluated with content analysis. In the hybrid education process, as a result of the infographic applications in the physics lesson, the technological competencies for educational purposes have developed in the students. As a result of students' effective use of infographic content in online and face-to-face educational applications, they have achieved advanced development in the dimensions of researching and questioning information, revealing the relationship between technological changes and science, and cognitive assimilation of information.