Solar thermal collectors, such as evacuated tube collectors (ETCs), are essential for harnessing renewable energy, yet their efficiency is often hindered by thermal losses and limited heat transfer. This study focuses on enhancing ETC performance for seawater desalination by using nanofluids as heat transfer fluids. These modifications aim to improve heat transfer rates, reduce thermal losses, increase the maximum temperature attainable, and minimize the collector area required. An experimental setup has been developed at Parul University in Vadodara, Gujarat, India. Key parameters such as air mass flow rate, inclination angle, water mass flow rate, nanofluid volume percentage, and screw conveyor speed were optimized to achieve ideal temperature levels. Results indicate that the optimal configuration for steam generation includes a high air mass flow rate and a 40° inclination angle for the ETC. Additionally, a water mass flow rate of 10 LPH and a screw conveyor speed of 30 rpm are crucial for optimal performance. Data collected showed the highest solar energy levels between 12 PM and 1 PM, which significant decreases post this peak period. These findings highlight the potential of nanomaterial‐based enhancements in improving the efficiency and cost‐effectiveness of solar thermal systems for renewable energy applications.