1997
DOI: 10.2214/ajr.169.2.9242759
|View full text |Cite
|
Sign up to set email alerts
|

Using endosonography to assess the effects of neoadjuvant therapy in patients with advanced esophageal cancer.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

4
28
2

Year Published

2000
2000
2014
2014

Publication Types

Select...
4
2
1

Relationship

0
7

Authors

Journals

citations
Cited by 41 publications
(34 citation statements)
references
References 11 publications
4
28
2
Order By: Relevance
“…The conclusions of this study, however, are similar to the results reported previously. 11,16 Laterza et al found that the overall accuracy of restaging EUS after CRT was poor, similar to what we found in the current study. The majority of patients in their study also were over staged during the restaging EUS examination, similar to our patients, especially in patients who achieved a complete response and in patients who had minimal disease.…”
Section: Discussionsupporting
confidence: 89%
See 1 more Smart Citation
“…The conclusions of this study, however, are similar to the results reported previously. 11,16 Laterza et al found that the overall accuracy of restaging EUS after CRT was poor, similar to what we found in the current study. The majority of patients in their study also were over staged during the restaging EUS examination, similar to our patients, especially in patients who achieved a complete response and in patients who had minimal disease.…”
Section: Discussionsupporting
confidence: 89%
“…19 A response to therapy was defined as a reduction of cross-sectional area by 50%, and this was validated by Chak and colleagues, who also showed a survival benefit for patients who achieved this level of response. 16,18,20 Bowrey et al evaluated a similar group of patients and found the same inaccuracies and unreliability of EUS for restaging esophageal carcinoma after CRT that we found. Their conclusion was to use the maximum tumor depth, in millimeters, as the measure to follow when monitoring response to CRT.…”
Section: Discussionsupporting
confidence: 82%
“…In an exploratory analysis, we attempted to assess the potential of EUS as a tool for outcome prediction to preoperative chemotherapy, evaluating the change in maximal tumour thickness with a decrease of X30% representing a response, the cut-off value utilised in RECIST and a simple response classifier. Response according to EUS and its correlation with outcomes, such as pathological response and survival, has previously been shown in small studies of neoadjuvant therapy for oesophageal cancer (Hirata et al, 1997;Chak et al, 2000;Willis et al, 2002;Masaho et al, 2005). In our analysis, there was no difference in OS between EUS responders and non-responders to preoperative chemotherapy and is likely to reflect the small number of patients.…”
Section: Discussionmentioning
confidence: 81%
“…Previous studies have attempted to determine the prognostic role of EUS for esophageal cancer treated with CRT by measuring the radial tumor thickness [30], total disease length [31], tumor volume [32] or tumor area [16,29,33,34,35]. In particular, a reduction in the cross-sectional area of tumor measured by EUS predicts the histopathologic response and prognosis in patients with esophageal cancer treated by neoadjuvant CRT [16,29,33,34,35].…”
Section: Introductionmentioning
confidence: 99%
“…In particular, a reduction in the cross-sectional area of tumor measured by EUS predicts the histopathologic response and prognosis in patients with esophageal cancer treated by neoadjuvant CRT [16,29,33,34,35]. However, no studies have attempted to evaluate the relation between prognosis and the reduction of esophageal cross-sectional tumor area on EUS after definitive CRT.…”
Section: Introductionmentioning
confidence: 99%